Publications by authors named "Raghuram A"

Article Synopsis
  • Many experimental setups in quantum science rely on laser fields for controlling states, but this control can suffer from issues related to optical phase noise.
  • Researchers introduced an optical feedforward technique to minimize laser phase noise during the stimulated Raman adiabatic passage for transferring ultracold RbCs molecules.
  • After conducting over 100 transfers on individual molecules, they achieved a notable transfer efficiency of 98.7(1)%, which is primarily constrained by the intensity of the lasers used.
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Background: Restorative justice (RJ) is an ethical lens that places emphasis on a community's connection and proliferative impact of actions, promoting communication and establishing methods for accountability. RJ practices can be applied on a spectrum, including proactive community-building practices, community discussions in response to an event, and restorative conferences addressing specific incidences of harm. This article describes an intervention that utilized RJ community-building practices within a medical education environment and evaluates its acceptability and feasibility.

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Article Synopsis
  • The study investigated factors linked to myopia progression and axial elongation in children with myopia.
  • It analyzed data from a trial comparing atropine treatment with a placebo, focusing on children aged 5 to <13 with specific refractive errors and other characteristics.
  • Results showed that younger children and those with higher initial myopia experienced more significant changes in refractive error and axial length, highlighting the need for treatments to slow progression in this at-risk group.
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Purpose: Concussed adolescents often report visual symptoms, especially for moving targets, but the mechanisms resulting in oculomotor deficits remain unclear. We objectively measured accommodative and vergence responses to a moving target in concussed adolescents and controls.

Methods: Thirty-two symptomatic concussed participants (mean age, 14.

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Background: Cardiovascular disease is the leading cause of death among women in the United States. Past research has highlighted the importance of the relationship between female-specific demographics and traditional risk factors. The present analysis aimed to identify the prevalence of modifiable risk factors in women attending a community cardiovascular health screening.

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  • The study investigates racial, ethnic, and sex disparities in enrollment for Pediatric Eye Disease Investigator Group (PEDIG) clinical studies, comparing the demographic data to the 2010 US Census for the pediatric population.
  • It analyzes data from PEDIG studies conducted in the US between 1997 and 2022, focusing on race, ethnicity, and sex of participants using various sources including published studies and ClinicalTrials.gov.
  • Results include statistical comparisons of enrollment percentages, identifying underrepresentation or overrepresentation of specific groups, and examining factors influencing these disparities.
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  • Congenital stationary night blindness (CSNB) is a genetic eye condition often linked to high myopia, which can lead to serious retinal issues, making understanding myopic progression crucial for potential treatments.
  • The study analyzed cases of CSNB associated with specific genetic variants in patients under 18 who had multiple eye measurements, using a mixed-effect model to track changes in myopia over time.
  • Results showed that individuals with CSNB are significantly myopic from birth and continue to experience worsening myopia as they grow, suggesting they may benefit from treatments aimed at slowing down myopia progression.
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Purpose: To measure and report the distribution of distance and near contrast sensitivity (CS) and low contrast visual acuity (LCVA) at 5% and 2.5% contrast in children aged 5-15 years with normal visual acuity (VA).

Design: Prospective, cross-sectional study.

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Introduction: Visual function deficits have been reported in adolescents following concussion. We compared vergence and accommodation deficits in paediatric and adolescent patients at a tertiary medical centre in the sub-acute (15 days to 12 weeks) and chronic (12 weeks to 1 year) phases of concussion recovery.

Methods: The study included patients aged 7 to <18 years seen between 2014 and 2021, who had a binocular vision (BV) examination conducted within 15 days and 1 year of their concussion injury.

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Purpose: Clinicians measure the near point of convergence (NPC) and the amplitude of accommodation (AA) from the spectacle plane, the bridge of the nose or the lateral canthus when assessing visual function. These values are compared to standard clinical criteria to diagnose vergence and accommodation deficits, despite varying reference points. This prospective study explored measuring relative to the spectacle plane and from the lateral canthus for NPC and monocular AA, and the resulting clinical implications of diagnosing visual deficits.

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Introduction: The selection of the most optimal fixation method for fractures of the distal femur, whether intramedullary nail (NL), lateral locking plate (PL), or nail/plate (NP) is not always clear. This study retrospectively evaluates surgical patients with distal femur fractures and introduces a pilot study using cluster analysis to identify the most optimal fracture fixation method for a given fracture type.

Methods: This is a retrospective cohort study of patients 18 years and older with an isolated distal femur fracture who presented to our Level-1 trauma center between January 1, 2012, and December 31, 2022, and obtained NL, PL, or NP implants.

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Introduction: In children with PRS, MDO is routinely performed to alleviate airway obstruction; however, it involves risk of injury to the MMN. We hypothesize that MMN palsy incidence following MDO, reported at 1-15%, is underestimated. This study investigates the true incidence of MMN palsy after MDO to better guide follow-up care and improve treatment of this complication.

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Burn injuries affect patients of all ages, and timely surgical debridement and excision commence to protect dermal vascularity and integrity, improve healing, and minimize scarring. Several tools may be used for burn wound excision, which is performed either tangentially or down to muscular fascia. Once wounds are optimized from a tissue viability and healing standpoint, coverage may be obtained through grafts or secondary intention healing for more superficial injuries.

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We present a rare case study of a 37-year-old man with a history of multiple prior snake bites who presented to the emergency department for treatment of a rattlesnake bite to his right hand. Upon examination, he was found to be mildly hypertensive and exhibited significant coagulation abnormalities. Initial treatment included six vials of Crotalidae polyvalent immune fab; however, his coagulopathy was so severe that he required an additional eight vials.

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Background: Patients undergoing postoncologic breast reconstruction can experience upper extremity (UE) functional deficits.

Objectives: In this study, we utilized the disabilities of the arm, shoulder, and hand (DASH) questionnaire to identify patient factors that impacted UE functional recovery.

Methods: Patients who underwent oncologic followed by reconstructive surgery by a single surgeon from 2014 to 2019 and completed the DASH survey were included.

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We present a simple motorized rotation mount for a half-wave plate that can be used to rapidly change the polarization of light. We use the device to switch a high power laser beam between different optical dipole traps in an ultracold atom experiment. The device uses a stepper motor with a hollow shaft, which allows a beam to propagate along the axis of the motor shaft, minimizing inertia and mechanical complexity.

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Objective: Surgeons shy away from using the Cabrol fistula (perigraft space to right atrium [RA] shunt) due to unfamiliarity, concern for persistent left-to-right shunting, and fear of "painting-over" anastomotic defects that will result in later problems. We review nearly 2 decades of experience with application of the Cabrol fistula in a large thoracic aortic practice, with emphasis on precise surgical techniques, early and late outcomes, and detailed radiographic analysis.

Methods: Operative records of all procedures in which the Cabrol fistula was used were retrieved and analyzed, with precise review of the details of construction of each Cabrol fistula and clinical and radiologic (echocardiographic and computed tomographic) patient follow-up.

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Background: This study aimed to determine if the energy delivered by the Gold laser impacted postoperative complication rates after adenoidectomy, tonsillectomy, or adenotonsillectomy.

Methods: A retrospective chart review identified 420 patients who met the criteria within the last five years. Indications for the surgeries included recurrent tonsillitis, obstructive sleep apnea, sleep-disordered breathing, adenoiditis, peritonsillar abscess, and other indications.

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Steady progress in time-domain diffuse optical tomography (TD-DOT) technology is allowing for the first time the design of low-cost, compact, and high-performance systems, thus promising more widespread clinical TD-DOT use, such as for recording brain tissue hemodynamics. TD-DOT is known to provide more accurate values of optical properties and physiological parameters compared to its frequency-domain or steady-state counterparts. However, achieving high temporal resolution is still difficult, as solving the inverse problem is computationally demanding, leading to relatively long reconstruction times.

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Importance: Controlling myopia progression is of interest worldwide. Low-dose atropine eye drops have slowed progression in children in East Asia.

Objective: To compare atropine, 0.

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Background: The pathology of primary osteoarthritis (OA) begins with structural cartilage damage, which initiates a self-propagating inflammatory pathway that further exacerbates cartilage deterioration. Current standard of care for knee primary OA involves treating the inflammatory symptoms to manage pain, which includes intra-articular (IA) injections of cortisone, an anti-inflammatory steroid, followed by a series of joint-cushioning hyaluronic acid gel injections. However, these injections do not delay the progression of primary OA.

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Background And Purpose: The degree of internal carotid artery (ICA) stenosis determined by criteria from the North American Symptomatic Carotid Endarterectomy Trial (NASCET) is not the most accurate index to assess distal flow compromise. Distal ICA perfusion is also determined by factors such as tandem carotid stenosis and collateral circulation. Quantification of end-organ ocular perfusion using non-invasive laser speckle flowgraphy (LSFG) may provide insights into distal ICA flow.

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Significance: Imaging through scattering media is critical in many biomedical imaging applications, such as breast tumor detection and functional neuroimaging. Time-of-flight diffuse optical tomography (ToF-DOT) is one of the most promising methods for high-resolution imaging through scattering media. ToF-DOT and many traditional DOT methods require an image reconstruction algorithm.

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Objectives: Mutations in the MYH11 gene result in smooth muscle cell dysfunction and are associated with familial thoracic aortic aneurysms and dissection. We describe a pediatric patient with a stroke and a pathogenic MYH11 IVS32G>A mutation, and a phenotype similar to ACTA2.

Methods: A proband girl with an acute ischemic stroke underwent genetic analysis and 7T high-resolution MRI.

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Objective: Brain aneurysms comprise different compartments that undergo unique biological processes. A detailed multimodal analysis incorporating 3D aneurysm wall enhancement (AWE), computational fluid dynamics (CFD), and finite element analysis (FEA) data can provide insights into the aneurysm wall biology.

Methods: Unruptured aneurysms were prospectively imaged with 7 T high-resolution MRI (HR-MRI).

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