Three-Dimensional Assessment and Comparison of the Maxillary Tuberosity Between Skeletal and Dental Class I and Class II Adults in Maxillary Third Molar Agenesis Using Cone Beam Computed Tomography: A Descriptive Cross-Sectional Human Study.

Aim And Objective: The objective of this study was to assess and compare the dimensions (width (W), height (H), and length (L)) of the tuberosity distal to maxillary permanent second molar in individuals with skeletal and dental Class I and Class II malocclusions who had maxillary third molar agenesis.

Methodology: Cone beam computed tomography (CBCT) was used to measure the left (L) and right (R) anatomical tuberosity dimensions in three dimensions using the WillMaster software (HDX WILL Corporation, Korea). The measurements were compared between Class I (n = 35) and Class II (n = 35) normo-hypodivergent adult subjects.

Influence of Different Mouth Rinsing Agents on Friction During Sliding Mechanics Between Orthodontic Metal Brackets and Stainless Steel Archwire: A Comparative In Vitro Study.

Aim and objectives The aim of this in-vitro study is to evaluate and compare the effect of various mouth rinsing agents on frictional resistance through sliding mechanics among orthodontic metal brackets and stainless steel (SS) archwire. Materials and methods Each group comprised 15 samples of maxillary first premolar pre-adjusted edgewise SS movable, un-bonded brackets (Koden Inc., United States) which were welded with a power arm, where 100 g of the load was suspended.

An In-Vitro Comparison of Shear Bond Strength and Adhesive Remnant Score Between Two Color Change Adhesives in Orthodontic Bonding With Reduced Curing Time Using Different High-Intensity Light Emitting Diode Units.

Aim And Objectives: This study aims to determine the effect on shear bond strength (SBS) and adhesive remnant score between two color change adhesives (CCAs) with reduced curing time using different high-intensity light emitting diode (LED) units.

Materials And Methods: A total of 108 human first maxillary premolar teeth were randomly allocated into three principal groups (n = 36) based on the type of adhesives used. The adhesives include two CCAs: TransbondPlus Color Change Adhesive (3M, St.

Effect of Charcoal, Probiotic, and Chlorhexidine Mouthwashes on Mechanical Properties and Surface Characterization of Ceramic-Coated Nickel-Titanium Orthodontic Arch Wires: A Comparative In-Vitro Study.

Aim And Objectives: To determine the impact on the mechanical properties and surface features of ceramic-coated nickel-titanium (CC-Ni-Ti) archwires when subjected to charcoal, probiotic, and chlorhexidine mouthwashes in in vitro conditions.

Materials And Methods: Eighty samples of 25 mm were cut from the posterior end of preformed maxillary 0.016'' CC-Ni-Ti super elastic archwires (Koden Company, USA) and distributed into four equal groups.

Effect of Sodium Flouride Mouthwash and Ozone-Infused Oil Pulling Solution With Coconut Oil on Mechanical Properties and Surface Characterization of Copper-Nickel-Titanium Orthodontic Archwires.

Aims And Objectives: To determine the impact on the mechanical properties and surface characteristics of prefabricated 0.016" copper-nickel-titanium (Cu-Ni-Ti) type 35C (Ormco Company, USA) archwires when subjected to 0.05% sodium fluoride (NaF) mouthwash (ACT Anti-Cavity Fluoride Mouthwash, Sanofi Company, USA) and ozone-infused oil-pulling solution with coconut oil (O) (O Essentials, Health Ranger Store, USA).

A Systematic Analysis of the Nasal Septum in Crooked Noses and Suggested Treatment Algorithm According to Preservation Rhinoplasty (PR) Principles.

Background: A deviated nose is a common problem among patients for both cosmetic and functional reasons. The correction remains a major challenge for the rhinoplasty surgeon. Unrecognized nasal septal deviations stand as the primary reason for failed rhinoplasty outcomes.

Adjustable tongue crib.

Thumb sucking and tongue thrusting habits are mostly counteracted and rehabilitated using a tongue crib. Most patients find the conventional crib difficult (due to its position and length) in the initial days of treatment and become uncooperative. Hence, few modifications are made to the traditional design of the tongue crib for easy adjustment of the crib height and angulation, which provides comfort to the patient.

"NIMS" nasal mucoperiosteal flap for sublabial trans-sphenoidal surgical defect repair: A new technique under microscope.

Background: CSF rhinorrhea is a known complication that may occur after cranial base surgery, especially the trans-sphenoidal approaches to sellar tumors. It may occur following both microscopic and endoscopic procedures. Over a period, the balance has tilted toward endoscopy due to development of pedicled Hadad flap.

Risk Factors, Vascular Lesion Distribution, Outcome and Recurrence of Strokes Due to Intracranial Atherosclerosis: One Year Data from Hyderabad Stroke Registry.

Background: Intracranial atherosclerotic stenosis (ICAS) is a common cause of ischemic stroke in Asian countries and probably in India.

Aim: The aim of this study was to describe the risk factors, distribution of vascular lesions, recurrence and outcome of stroke due to ICAS.

Methodology: A total of 100 consecutive patients of ischemic stroke due to ICAS were enrolled prospectively from January 1, 2015, to December 31, 2015, and followed for 1 year for treatment compliance and recurrence.

Purification and characterization of glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) from pea seeds.

Glyceraldehyde-3-phosphate dehydrogenase [GAPDH, NAD + oxidoreductase (phosphorylating) 1.2.1.

An observational study of the quality of care for chronic kidney disease: a Buffalo and Albany, New York metropolitan area study.

Background: The database of a major regional health insurer was employed to identify the number and frequency of covered patients with chronic kidney disease (CKD). We then examined the characteristics of their care as defined, in part, by the frequency of physician visits and specialty referral, the characteristics of laboratory testing and total costs as indices of the quality of care of the subject population.

Methods: This retrospective, cross-sectional study analyzed insurance claims, laboratory results and medication prescription data.

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.

Background: Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These characteristics correlate with a distinct nuclear architecture, epigenetic signatures enriched for active chromatin marks and hyperdynamic binding of structural chromatin proteins. Recently, several chromatin-related proteins have been shown to regulate ESC pluripotency and/or differentiation, yet the role of the major heterochromatin proteins in pluripotency is unknown.

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

Chromatin compaction mediates progenitor to post-mitotic cell transitions and modulates gene expression programs, yet the mechanisms are poorly defined. Snf2h and Snf2l are ATP-dependent chromatin remodelling proteins that assemble, reposition and space nucleosomes, and are robustly expressed in the brain. Here we show that mice conditionally inactivated for Snf2h in neural progenitors have reduced levels of histone H1 and H2A variants that compromise chromatin fluidity and transcriptional programs within the developing cerebellum.

Higher chromatin mobility supports totipotency and precedes pluripotency in vivo.

The fusion of the gametes upon fertilization results in the formation of a totipotent cell. Embryonic chromatin is expected to be able to support a large degree of plasticity. However, whether this plasticity relies on a particular conformation of the embryonic chromatin is unknown.

Rhizobium subbaraonis sp. nov., an endolithic bacterium isolated from beach sand.

Two strains (JC85(T) and JC108) of Gram-stain-negative, motile bacteria were isolated from endolithic beach sand samples on an oligotrophic medium. Based on the 16S rRNA gene sequence analysis, both strains were identified as belonging to the genus Rhizobium. Strain JC108 had 16S rRNA gene sequence similarity of 100 % with Rhizobium pusense NRCPB10(T) and formed a cluster with this strain.

Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cells.

DNA double-strand breaks (DSBs), the most hazardous DNA lesions, may result in genomic instability, a hallmark of cancer cells. The main DSB repair pathways are non-homologous end joining (NHEJ) and homologous recombination (HR). In mammalian cells, NHEJ, which can lead to inaccurate repair, predominates.

Nuclear gyrB encodes a functional subunit of the Plasmodium falciparum gyrase that is involved in apicoplast DNA replication.

The DNA replication machinery of the Plasmodium falciparum apicoplast is a validated drug target. Nuclear-encoded gyrase subunits are predicted to play a critical role in maintaining DNA topology during the D-loop/bi-directional ori replication process of the parasite. We show the presence of P.

Eyelid metastasis from lung carcinoma.

A 74-year-old man presented with a 4-month history of swelling in the right upper lid. Biopsy of the lesion showed moderate to poorly differentiated invasive squamous cell carcinoma. He was recently diagnosed with squamous carcinoma of the lung with similar histology to the eyelid lesion.

Multiple replication origins within the inverted repeat region of the Plasmodium falciparum apicoplast genome are differentially activated.

The 35 kb circular genome (plDNA) of the Plasmodium falciparum apicoplast replicates by the bidirectional ori/D-loop mechanism. PlDNA replication was previously shown to initiate within the inverted repeat (IR) region of the apicoplast genome [Williamson DH, Preiser PR, Moore PW, McCready S, Strath M, Wilson RJM (Iain). The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms.

Terson's syndrome presenting as an ophthalmic emergency.

Purpose: To report an unusual case of Terson's syndrome caused by a ruptured intracranial aneurysm presenting as an ophthalmic emergency with visual loss, without any neurological features at the time of presentation.

Methods: Case report. A 38-year-old man was referred to the eye emergency department with sudden loss of vision in both eyes.

Dietary factors as determinants of hypertension: A case control study in an urban Indian population.

Hypertension, an important risk factor for coronary heart disease (CHD), is often associated with certain dietary habits which can either adversely affect or decrease blood pressure. Several Western studies have documented the role of diet, especially excess energy, both quality and quantity of fat and salt, in the aetiopathogenesis of chronic diseases such as hypertension, diabetes and CHD. Indians are particularly susceptible to these chronic diseases.