Dentistry students' opinion toward Biochemistry course and its relevance in clinical practice in Chennai, India.

Biochemistry is a subject that is essential to understand the molecular basis of a disease, its diagnosis, and prognosis. However, study of biochemistry in dentistry at the undergraduate level is considered to be much teacher-oriented and the students show a lackluster attitude toward the subject. This questionnaire study is carried out to understand the perception of dental students in studying biochemistry and its relevance in dental practice.

Osseointegration.

Direct rigid fixation of the implant into jawbones has become an accepted and proven treatment for edentulism. This paper reviews the concept of osseointegration.

Mandibular advancement device for obstructive sleep apnea: An overview.

This paper presents an overview of mandibular advancement device (MAD). The primary purpose of MAD is to move the mandible forwards relative to maxilla in ordered to widen the airway to prevent to closure.

Comprehensive mutation analysis of PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 genes is suggestive of a non- neoplastic nature of phenytoin induced gingival overgrowth.

Background: Dilantin sodium (phenytoin) is an antiepileptic drug, which is routinely used to control generalized tonic clonic seizure and partial seizure episodes. A few case reports of oral squamous cell carcinomas arising from regions of phenytoin induced gingival overgrowth (GO), and overexpression of mitogenic factors and p53 have presented this condition as a pathology with potential to transform into malignancy. We recently investigated the genetic status of p53 and H-ras, which are known to be frequently mutated in Indian oral carcinomas in GO tissues and found them to only contain wild type sequences, which suggested a non-neoplastic nature of phenytoin induced GO.