Productivity improvement in l-sorbose biosynthesis by fedbatch cultivation of Gluconobacter oxydans.

The effect of increased (100, 200 and 300 gl(-1)) initial sorbitol concentrations (S0) was investigated in the sorbitol to sorbose bioconversion process. Batch cultivations with a S0 of 100, 200 and 300 gl(-1) were completed at 10, 14 and 24 h with a corresponding overall sorbose productivity of 10.1, 14.