Association between APOE genotypes and metabolic syndrome in a middle aged and elderly Urban South Indian population.

Background: This study examines the association between apolipoprotein E (APOE) genotypes and metabolic syndrome (MetS) in an older urban population in South India, as part of the Tata Longitudinal Study on Aging.

Methods: A total of 618 participants aged 45 and above were analyzed cross-sectionally for the association between APOE carrier status and MetS (based on both NCEP ATP III and Consensus criteria).

Results: Despite the high prevalence of MetS observed in this cohort (51.

Sex-specific differences in the association between APOE genotype and metabolic syndrome among middle-aged and older rural Indians.

Background: Metabolic syndrome (MetS), characterized by elevated blood pressure, high blood glucose, excess abdominal fat, and abnormal cholesterol or triglyceride levels, significantly increases the risk of various non-communicable diseases. This study focuses on understanding the sex-specific association between Apolipoprotein E (APOE) polymorphism and MetS among middle-aged and older adults in rural southern India.

Methods: This cross-sectional study utilized data from the Centre for Brain Research-Srinivaspura Aging, Neuro Senescence, and COGnition (CBR-SANSCOG) study.

Post-Stroke Recrudescence: A Case Report and Literature Review.

Post-stroke recrudescence (PSR) is a clinical entity characterized by the acute transient recurrence of previously recovered focal stroke deficits. Various names have been used to describe PSR, which further complicates its diagnosis. Increased awareness of this condition is crucial for preventing inappropriate management and unnecessary testing.

Tracking the Progression and Influence of Beta-Amyloid Plaques Using Percolation Centrality and Collective Influence Algorithm: A Study Using PET Images.

Background: The study of brain networks, particularly the spread of disease, is made easier thanks to the network theory. The aberrant accumulation of beta-amyloid plaques and tau protein tangles in Alzheimer's disease causes disruption in brain networks. The evaluation scores, such as the mini-mental state examination (MMSE) and neuropsychiatric inventory questionnaire, which provide a clinical diagnosis, are affected by this build-up.