Seroprevalence of in Cattle in Southern Egypt: Do Milk and Serum Samples Tell the Same Story?

is an intracellular protozoan parasite of veterinary and public health importance. Infection may lead to abortion in susceptible pregnant animals and women, and potentially fatal health complications in immunocompromised individuals. In this study, we aimed to provide an update on the seroprevalence of, and risk factors for, antibodies in cattle from Qena, southern Egypt.

Exposure to Species, , and Species in Recently Imported Camels from Sudan to Egypt: Possible Threats to Animal and Human Health.

Brucellosis and coxiellosis/Q fever are bacterial infections caused by species and , respectively; camels are highly susceptible to both pathogens. Trichinellosis is a parasitic infection caused by various nematode species. Reportedly, camels are susceptible to experimental infection with spp.

Tick-borne pathogens in camels: A systematic review and meta-analysis of the prevalence in dromedaries.

Published data on tick-borne pathogens (TBPs) in camels worldwide have been collected to provide an overview of the global prevalence and species diversity of camelid TBPs. Several TBPs have been detected in dromedary camels, raising concerns regarding their role as natural or maintenance hosts for tick-borne pathogens. Insubstantial evidence exists regarding the natural infection of camels with Babesia spp.

The influence of risk factors on bovine leukemia virus infection and proviral load in egyptian cattle.

Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leucosis (EBL), which affects cattle globally. In Egypt, BLV control strategies have been ignored because of the shortage of BLV research studies and the silent infection in most animals. This study aimed to identify the risk factors associated with the prevalence of BLV among dairy and beef cattle from six different geographic and climatic provinces in Egypt.

Evaluation of Clinical and Biochemical Traits in Egyptian Barki Sheep with Different Growth Performances.

The Barki sheep industry is becoming increasingly important in Egypt because of the high quality of their meat and wool. This sheep breed is also commonly known for its resistance to arid and harsh environmental conditions. Such characteristics can be exploited in solving the problematic situation of inadequate animal protein for human consumption, particularly under climatic changes.

Seroprevalence and risk factors analysis of and in cattle of Beheira, Egypt.

Introduction: and are closely related obligate intracellular protozoan parasites. They are considered to be the major causes of infectious abortions and congenital abnormalities in livestock worldwide resulting in huge economic losses. Currently, there are no reports on the prevalence of neosporosis or toxoplasmosis in cattle in Beheira, Egypt's most important region for cattle industry.

High relatedness of bioinformatic data and realistic experimental works on the potentials of and cathepsin L1 as a diagnostic and vaccine antigen.

Introduction: Fascioliasis is a parasitic foodborne disease caused by the liver flukes, and . Such parasites cause serious illness in numerous domestic animals and also in humans. Following infection, the parasite secretes a variety of molecules that immediately interact with the host immunity to establish successful infection.

Exploiting the Macrophage Production of IL-12 in Improvement of Vaccine Development against and Infections.

Toxoplasmosis and neosporosis are major protozoan diseases of global distribution. is the cause of toxoplasmosis, which affects almost all warm-blooded animals, including humans, while induces neosporosis in many animal species, especially cattle. The current defective situation with control measures is hindering all efforts to overcome the health hazards and economic losses of toxoplasmosis and neosporosis.

and Antibodies in Dogs and Cats from Egypt and Risk Factor Analysis.

Background: and are major protozoan parasites of worldwide distribution and significance in veterinary medicine and, for , in public health. Cats and dogs, as final hosts for and respectively, have a key function in environmental contamination with oocysts and, thus, in parasite transmission. Very little is known about the prevalence of infections in dogs and cats in Egypt, and even less about the prevalence of in the same hosts.

Seroprevalence of Specific Antibodies to , , and spp. in Sheep and Goats in Egypt.

Toxoplasmosis, neosporosis, and brucellosis are devastating diseases causing infectious abortion and, therefore, substantial economic losses in farm animals. Toxoplasmosis and neosporosis are caused by the intracellular protozoan parasites () and (), respectively. Brucellosis is a bacterial disease caused by numerous species in multiple hosts.

Seroprevalence of and in camels recently imported to Egypt from Sudan and a global systematic review.

Introduction: Toxoplasma gondii and Neospora caninum are closely related intracellular protozoan parasites of medical and veterinary concern by causing abortions and systemic illness. Limited or ambiguous data on the prevalence of T. gondii and N.

Prevalence of and Antibodies and DNA in Raw Milk of Various Ruminants in Egypt.

The prevalence of and antibodies in raw milk samples was estimated in different ruminants and Egyptian governorates. Of 13 bulk milk samples tested by ELISA, five (38.5%) were positive for antibodies to , and two samples were additionally positive for antibodies to , resulting in a seroprevalence of 15.

Genetic Disruption of Toxoplasma gondii peroxiredoxin (TgPrx) 1 and 3 Reveals the Essential Role of TgPrx3 in Protecting Mice from Fatal Consequences of Toxoplasmosis.

is a worldwide protozoan parasite that endangers human health and causes enormous economic losses to the animal production sector. A safe and effective vaccine or treatment is needed to reduce these hazards. In this study, we revealed the cyto-nuclear and mitochondrial localization of TgPrx1 and TgPrx3 proteins, respectively.

Exposure to in Asian Elephants () in Thailand.

is the causative agent of toxoplasmosis in humans and various animal species worldwide. In Thailand, seroprevalence studies on have focused on domestic animals, and information on infections in Asian elephants () is scarce. This study was conducted to determine the seroprevalence of infection in archival sera collected from 268 elephants living in Thailand.

Transcriptomic Analysis of the Effects of Chemokine Receptor CXCR3 Deficiency on Immune Responses in the Mouse Brain during Infection.

The obligate intracellular parasite infects warm-blooded animals, including humans. We previously revealed through a whole-brain transcriptome analysis that infection with in mice causes immune response-associated genes to be upregulated, for instance, chemokines and chemokine receptors such as CXC chemokine receptor 3 (CXCR3) and its ligand CXC chemokine ligand 10 (CXCL10). Here, we describe the effect of CXCR3 on responses against infection in the mouse brain.

Macrophage Stimulation as a Useful Approach for Immunoscreening of Potential Vaccine Candidates Against Toxoplasma gondii and Neospora caninum Infections.

Toxoplasmosis and neosporosis are protozoan diseases that adversely affect the medical and additionally veterinary sectors, respectively. Toxoplasmosis is caused by Toxoplasma gondii which infects almost all warm-blooded animals including humans. While, neosporosis is caused by Neospora caninum, which induces infection in many animal species particularly in cattle.

Comparative Evaluation of Four Potent Diagnostic Antigens Using Immunochromatographic Assay for Detection of Specific Antibody in Cattle.

is an intracellular protozoan parasite responsible for numerous abortion outbreaks and neonatal abnormalities in cattle. Rapid and accurate diagnosis is critical for control owing to the lack of vaccine or drug-based control strategies. Herein, we evaluated the performance of four frequently used antigens in the diagnosis of infection using immunochromatographic tests (ICTs) as a rapid, affordable, and field applicable tool.

Vaccination with GRA6 Interrupts the Vertical Transmission and Partially Protects Dams and Offspring against Infection in Mice.

Vaccination is the mainstay of preventative measures for numerous infectious diseases. infection induces storms of abortion in pregnant cows and ewes, resulting in drastic economic losses because of fetal losses and culling of the dams. Herein, we evaluated the potential of recombinant protein of dense granule protein 6 fused with glutathione--transferase (NcGRA6+GST) as a vaccine candidate against neosporosis in a pregnant mouse model.

Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway.

infects almost all warm-blooded animals, including humans, leading to both cellular and humoral immune responses in the host. The virulence of is strain specific and is defined by secreted effector proteins that disturb host immunity. Here, we focus on nuclear factor-kappa B (NFκB) signaling, which regulates the induction of T-helper type 1 immunity.

Urological detection of specific antibodies against Neospora caninum infection in mice: A prospect for novel diagnostic approach of Neospora.

The intracellular protozoan parasite Neospora caninum is incriminated to induce drastic economic losses in both livestock and pet animal industries. Neosporosis is primarily characterized by abortion in cattle and paralytic symptoms in dogs. Because there are no effective treatments or vaccines, diagnosis is critical for Neospora control.