Publications by authors named "Rafi Matin"
Transl Psychiatry
April 2024
Article Synopsis
- Deep brain stimulation (DBS) is a treatment that alters brain connectivity to improve outcomes in patients with various neurological, developmental, and psychiatric disorders, but the exact mechanisms behind its effectiveness are still unclear.
- A systematic review of 407 studies showed that DBS generally leads to positive behavioral outcomes, especially in models of psychiatric disorders through changes in brain chemistry and activity, and in movement disorders by affecting the dopaminergic system.
- While this research has increased understanding of disease mechanisms and the effects of DBS, translating these findings to clinical applications remains challenging, and further exploration of the underlying mechanisms is needed.
Neurotherapeutics
April 2024
Article Synopsis
- Epilepsy affects many people, and about one-third of those with the condition don't find relief from two standard anti-seizure medications, leading to a focus on neurostimulation options for treatment.*
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- Neurostimulation methods like Vagus Nerve Stimulation (VNS), Deep Brain Stimulation (DBS), and Responsive Neurostimulation (RNS) are available, with some being FDA-approved and showing potential benefits in reducing seizures for patients with drug-resistant epilepsy.*
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- The discussion highlights the effectiveness of these methods, their uses in specific populations, and their implications based on neuroimaging data, providing insights into how they target different brain areas to alleviate seizures.*
