Electrochemical advanced oxidation combined to electro-Fenton for effective treatment of perfluoroalkyl substances "PFAS" in water using a Magnéli phase-based anode.

Per-and polyfluoroalkyl substances (PFAS), known as "forever chemicals", are posing a considerable threat to human health and the environment, that conventional treatment methods are unable to treat. In recent years, electrochemical advanced oxidation emerged as a promising technology for the degradation of recalcitrant pollutants such as PFAS. This work reports the degradation of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), using a Magnéli phase-based anode type TiO by electro-oxidation and electro-oxidation combined with electro-Fenton.

On the in situ 3D electrostatic directed assembly of CdSe/CdZnS colloidal quantum nanoplatelets towards display applications.

Hypothesis: Due to their unique quantum yield and photostability performances, quantum nanoplatelets are very promising building blocks for future generations of displays. The directed assembly of such colloidal nano-objects in the shape of micro-pixels is thus the next mandatory step to reach this goal. Selectively trapping them on electrostatically charged patterns by nanoxerography could be a versatile and appealing strategy but requires a full understanding of the assembly mechanisms in order to make the most of their integration.

Synthesis of hybrid colloidal nanoparticles for a generic approach to 3D electrostatic directed assembly: Application to anti-counterfeiting.

Hypothesis: The capability of making 3D directed assembly of colloidal nanoparticles on surfaces, instead of 2D one, is of major interest to generate, tailor, and enhance their original functionalities. The nanoxerography technique, i.e.

Sub-stoichiometric titanium oxide (TiO) as a suitable ceramic anode for electrooxidation of organic pollutants: A case study of kinetics, mineralization and toxicity assessment of amoxicillin.

Electrochemical degradation of aqueous solutions containing antibiotic amoxicillin (AMX) has been extensively studied in an undivided electrolytic cell using a sub-stoichiometric titanium oxide (TiO) anode, elaborated by plasma deposition. Oxidative degradation of AMX by hydroxyl radicals was assessed as a function of applied current and was found to follow pseudo-first order kinetics. The use of carbon-felt cathode enhanced oxidation capacity of the process due to the generation of HO.

A Soft 3D Acoustic Metafluid with Dual-Band Negative Refractive Index.

Spherical silica xerogels are efficient acoustic Mie resonators. When these sub-wavelength inclusions are dispersed in a matrix, the final metafluid may display a negative acoustic refractive index upon a set of precise constraints concerning material properties, concentration, size, and dispersity of the inclusions. Because xerogels may sustain both pressure and shear waves, several bands with negative index can be tailored.

Impact of polydispersity on multipolar resonant scattering in emulsions.

The influence of size polydispersity on the resonant acoustic properties of dilute emulsions, made of fluorinated-oil droplets, is quantitatively investigated. Ultrasound attenuation and dispersion measurements on various samples with controlled size polydispersities, ranging from 1% to 13%, are found to be in excellent agreement with predictions based on the independent scattering approximation. By relating the particle-size distribution of the synthesized emulsions to the quality factor of the predicted multipolar resonances, the number of observable acoustic resonances is shown to be imposed by the sample polydispersity.

VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy.

Bevacizumab, an anti-vascular endothelial growth factor (VEGF-A) antibody, is used in metastatic colorectal carcinoma (CRC) treatment, but responses are unpredictable. Vascular endothelial growth factor is alternatively spliced to form proangiogenic VEGF(165) and antiangiogenic VEGF(165)b. Using isoform-specific enzyme-linked immunosorbent assay and quantitative polymerase chain reaction, we found that over 90% of the VEGF in normal colonic tissue was VEGF(xxx)b, but there was a variable upregulation of VEGF(xxx) and downregulation of VEGF(xxx)b in paired human CRC samples.

Electroinsertion and activation of the C-terminal domain of colicin A, a voltage gated bacterial toxin, into mammalian cell membranes.

The C-terminal fragment of colicin, a protein that is highly soluble in aqueous solution, is spontaneously and irreversibly inserted into the membranes of mammalian cells, which are locally permeabilized by a transmembrane voltage increase. Insertion is detected by immunodetection. This is obtained by mixing the protein with electropermeabilized cells.

Pharmacokinetic study of 45Ca administered intravenously following intramuscular injection of vitamin D3 or 25-hydroxyvitamin D3 in early weaned lambs.

The objective of this study was to evaluate the pharmacokinetic parameters of 45Ca administered intravenously at a dose of 50 microCi in young lambs. The experiment was performed on 18 female lambs allocated to three treatments. Six animals received intravenous calcium only; six received intramuscularly vitamin D3 8 days prior to the administration of calcium; and six received intramuscularly 25-hydroxyvitamin D3 5 days prior to the administration of calcium.

Control of lipid membrane stability by cholesterol content.

Cholesterol has a concentration-dependent effect on membrane organization. It is able to control the membrane permeability by inducing conformational ordering of the lipid chains. A systematic investigation of lipid bilayer permeability is described in the present work.

Tertiary structure-dependence of misfolding substitutions in loops of the maltose-binding protein.

We previously identified and characterized amino acid substitutions in a loop connecting helix I to strand B, the alphaI/betaB loop, of the N-domain that are critical for in vivo folding of the maltose-binding protein (MalE31). The tertiary context-dependence of this mutation in MalE folding was assessed by probing the tolerance of an equivalent alphabeta loop of the C-domain to the same amino acid substitutions (MalE219). Moving the loop mutation from the N- to the C-domain eliminated the in vivo misfolding step that led to the formation of inclusion bodies.

Surface charge control of electropermeabilization and glycophorin electroinsertion with 1,2-diacyl-sn-glycero-3-phosphocholine (lecithin) liposomes.

Back insertion of a solubilized membrane protein, glycophorin A, has been obtained in lipid multilamellar vesicles by applying calibrated electric field pulses on a lipid/protein mixture. Experimental evidence for insertion is given by means of immunofluorescence. Insertion was obtained only under field conditions that induced the leakage of a soluble hydrophilic molecule, calcein, which was trapped between the lipid layers.

Electroinsertion of glycophorin A in interdigitation-fusion giant unilamellar lipid vesicles.

Previously we demonstrated that transmembrane back insertion of glycophorin A, a solubilizable intrinsic protein, can be obtained in dipalmitoylphosphatidylcholine multilamellar vesicles, MLVs, by electropulsation (Raffy, S., and Teissié, J. (1995) Eur.

Insertion of glycophorin A, a transmembraneous protein, in lipid bilayers can be mediated by electropermeabilization.

Transmembraneous back-insertion of a solubilized membrane protein, glycophorin A, has been obtained in 1,2 dipalmitoyl-sn-glycero-3-phosphocholine (Pam2GroPCho) cell-size-like liposomes by submitting the lipid/protein mixture to calibrated electric field pulses. Field conditions which are prone to trigger glycophorin insertion are similar to those which mediate lipid layer electropermeabilization. The efflux of calcein, trapped in the liposomes during their preparation, was observed only when field strength is higher than 1.