Vascular Complications after Facial Filler Injection: A Literature Review and Meta-analysis.

Vascular occlusion during the injection of facial fillers is uncommon, but can result in serious adverse events, including necrosis, blindness, and stroke. We explored factors that influence the frequency and severity of vascular complications during filler injections. This was a meta-analysis that included case reports and case series published during the years 2004 to 2016 describing patients who experienced any type of vascular complication after an aesthetic procedure.