Publications by authors named "Raffaella Ribaldone"
Article Synopsis
- - This study analyzed HPV genotype distribution in high-grade vaginal intraepithelial neoplasia (VaIN) patients from two Italian hospitals over 19 years, finding HPV DNA in 94.4% of cases.
- - HPV 16 was the most common strain detected, especially in VaIN3 cases, while other notable strains included HPV 58, HPV 73, and HPV 31.
- - A significant portion of infections were single-strain, and many were covered by the nine-valent HPV vaccine, suggesting that vaccination could greatly decrease VaIN incidence.
Vulvovaginal atrophy (VVA) has an impact on the quality of life (QoL) of women. This post hoc analysis of the EVES study provides an overview of the QoL in postmenopausal Italian women in relation with VVA severity. We included 1066 women attending menopause/gynaecologic centres.
View Article and Find Full Text PDFObjective: To evaluate the relationships between excisional treatment for high-grade cervical intra-epithelial neoplasia (CIN2+) and obstetric outcomes in terms of preterm delivery risk, premature rupture of membrane (PROM) and type of delivery, and between pre-term delivery and the type of excisional technique (radio frequency excision, laser conization).
Methods: This was a retrospective study of the obstetric outcomes of 2316 women aged 25-45 years who underwent excisional treatment for CIN2+ at the Obstetric and Gynecological Clinic of Ospedale Maggiore della Carità in Novara and at the Obstetric and Gynecological Department of Ospedale Sant'Anna in Torino in the period 2005-2014 and were evaluated until April 2016, and 57,937 untreated women of the same age, from the same centers.
Results: After treatment, 320 women had at least one pregnancy leading to delivery after a mean of 3.
Purpose: The aim of study was to investigate factors predicting persistence or relapse of disease after cervical conisation for high-grade squamous intraepithelial lesions (CIN 2 or 3).
Methods: The study involved 78 women with high-grade squamous intraepithelial lesions, conservatively treated with loop electroexcision procedure for cervical conisation and subsequent with CO(2) laser-vaporisation of the cervical bed. Histological specimens were totally included and examined by an experienced pathologist.
Aims: The purpose of the study was to investigate the transplacental transmission of the human polyomaviruses JCV and BKV.
Methods: Urine and blood samples from 300 pregnant women underwent cytological analysis to search for 'decoy cells', nested PCR to identify presence and genotype of isolated polyomaviruses, and sequence analysis of the transcription control region. Nested PCR was also used to study the umbilical cord blood of all their newborns.
Splenic rupture with intraperitoneal hemorrhage is a fatal condition that is rarely encountered during the third trimester of pregnancy; its pathogenetic mechanisms and causes are largely unknown. We report a case of splenic rupture in a pregnant woman that caused the death of the mother and child. The patient was a carrier of double heterozygosis for hemoglobin C/beta-thalassemia.
View Article and Find Full Text PDFObjective: To evaluate the interobserver reliability of colposcopy and the prediction of final histologic results.
Materials And Methods: Visibility of the squamocolumnar junction, presence and grading of atypical transformation zone (ATZ), and presence and grading of cervical intraepithelial neoplasia (CIN) were assessed by nine expert colposcopists in 100 cervigrams. Pairwise kappa, group kappa, and class-specific kappa values were computed.