Publications by authors named "Raffaella DeSantis"
Article Synopsis
- A study evaluated whether a 1-day/week regimen of trimethoprim/sulfamethoxazole can effectively prevent Pneumocystis pneumonia (PCP) in children undergoing cancer treatment, in contrast to more frequent dosing schedules recommended.
- The study involved 20 pediatric hematology-oncology centers in Italy, surveying 2466 patients with various cancer diagnoses, where 27.9% were on the 1-day regimen, and only 0.08% experienced PCP cases, both from the 2-day/week group.
- The findings suggest that a simplified 1-day prophylaxis may be adequate for PCP prevention in these patients, which could influence similar approaches for other immunocompromised individuals beyond just cancer care
Background: Peripheral blood stem cells (PBSCs) are the preferred source in autologous transplantation. We assessed prospectively the efficacy of mobilization in pediatric patients and risk factors associated with its failure.
Study Design And Methods: Patients, aged 0 to 17 years, needing a first collection of PBSCs for autologous stem cell transplantation were eligible.