Publications by authors named "Raffaele Rinaldi"
Impact of burden and distribution of aortic valve calcification on the hemodynamic performance and procedural outcomes of a self-expanding, intra-annular transcatheter aortic valve system.
Annunziata Nusca Michele Mattia Viscusi Simone Circhetta Valeria Cammalleri Fabio Mangiacapra Raffaele Rinaldi
Int J Cardiovasc Imaging
December 2024
Article Synopsis
- Aortic valve calcification (AVC) is examined as a predictor for complications in transcatheter aortic valve implantation (TAVI), with a focus on its impact on intra-annular devices.
- Patients with high AVC have a higher risk of developing mild to severe paravalvular leak (PVL) and conduction disorders requiring pacemaker implantation, indicating AVC's significant role in post-TAVI outcomes.
- The study found that higher AVC levels predict poor 30-day clinical outcomes after TAVI, highlighting the importance of assessing AVC to improve patient management.
Article Synopsis
- Coronary chronic total occlusions (CTOs) are common challenges in percutaneous coronary interventions (PCI), making them a significant focus in clinical settings.
- Despite mixed results from randomized trials on the benefits of recanalizing CTOs, the number of these procedures has notably increased due to advancements in techniques and training.
- This review aims to summarize the clinical outcomes, technical aspects, and safety concerns related to CTO revascularization to assist clinicians in their daily cath-lab practices.
Article Synopsis
- - Takotsubo syndrome (TTS) is a temporary heart condition with abnormal wall motion caused by various factors like inflammation, stress hormones, and vascular issues, often mimicking symptoms of a heart attack but typically lacks coronary artery blockage.
- - Recent studies suggest that TTS and coronary artery disease (CAD) may coexist in some patients, challenging the belief that they are entirely separate conditions and potentially affecting treatment outcomes.
- - The review aims to explore the complex relationship between TTS and CAD, focusing on shared mechanisms, diagnosis challenges, and effective treatment strategies for both conditions.
Article Synopsis
- The study examines how different levels of post-procedure cardiac troponin (cTn) elevation relate to incomplete revascularization (IR) in patients who have undergone percutaneous coronary intervention (PCI).
- A total of 1,061 patients were evaluated, with 23.4% experiencing IR and over half showing major myocardial injury; higher pre-procedure SYNTAX scores correlated with increased risk for both conditions.
- Results indicate that patients with IR combined with significant cTn elevation had a notably higher risk of major adverse cardiac events (MACE) over two years, emphasizing that periprocedural myocardial injury may signal a high-risk group for long-term complications.
Article Synopsis
- Percutaneous coronary intervention (PCI) can lead to type 4a myocardial infarction (MI), which increases mortality risk, particularly in patients with chronic coronary syndrome (CCS).
- A study involving 442 patients evaluated the angiography-derived hemodynamic index (ADDED) to predict type 4a MI by measuring myocardial risk and lesion severity during single-vessel PCI.
- Results indicated that a higher ADDED index was linked to a greater occurrence of type 4a MI, with values above 5.25 serving as a strong predictor, suggesting that this index could help identify high-risk patients who might benefit from additional preventive strategies.