Publications by authors named "Raffaela Magris"
Background: Pepsinogen (PG) II (PGII) is a serological marker used to estimate the risk of gastric cancer but how PGII expression is regulated is largely unknown. It has been suggested that PGII expression, from the (Progastricsin) gene, is regulated by microRNAs (miRNA), but how PGII levels vary with infection and miRNAs genotype remains unclear.
Methods: Serum levels of PGI and PGII were determined in 80 patients with gastric cancer and persons at risk for gastric cancer (74 first-degree relatives of patients, 62 patients with autoimmune chronic atrophic gastritis, and 2 patients with dysplasia), with and without infection.