Publications by authors named "Rafal Staros"
In a living organism, cancer cells function in a specific microenvironment, where they exchange numerous physical and biochemical cues with other cells and the surrounding extracellular matrix (ECM). Immune evasion is a clinically relevant phenomenon, in which cancer cells are able to direct this interchange of signals against the immune effector cells and to generate an immunosuppressive environment favoring their own survival. A proper understanding of this phenomenon is substantial for generating more successful anticancer therapies.
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- PTLD is a serious complication that can occur after organ transplantation, and its risk level varies between kidney and liver transplant recipients.
- In a study involving nearly 4,000 transplant patients, PTLD was diagnosed more frequently in liver transplant recipients compared to kidney transplant recipients, with different factors influencing the onset and outcomes for each group.
- Key findings include that older age, male sex, and the use of tacrolimus increase the risk of PTLD, while younger liver transplant recipients had better survival rates and higher chances of complete remission compared to kidney transplant recipients.