A new form of neurotherapy for a patient with anxiety disorder and anomic aphasia after neurosurgery for a ruptured brain aneurysm post-COVID-19.

Introduction And Objective: The aim of this study is to evaluate the effectiveness of a new, neuromarker-based form of neurotherapy for a patient with anxiety disorders and anomic aphasia after a neurosurgical operation for a ruptured brain aneurysm of the left middle cerebral artery (MCA), detected after COVID-19.

Case Report: A 78-year-old right-handed patient, not previously treated for any chronic diseases except stage II hypertension, contracted COVID-19, confirmed by real time RT- PCR. He was treated on an outpatient basis.

Assessment of the Suitability of Coke Material for Proppants in the Hydraulic Fracturing of Coals.

To enhance the extraction of methane gas from coal beds, hydraulic fracturing technology is used. However, stimulation operations in soft rocks, such as coal beds, are associated with technical problems related mainly to the embedment phenomenon. Therefore, the concept of a novel coke-based proppant was introduced.

Transcriptomic Studies on Intracranial Aneurysms.

Intracranial aneurysm (IA) is a relatively common vascular malformation of an intracranial artery. In most cases, its presence is asymptomatic, but IA rupture causing subarachnoid hemorrhage is a life-threating condition with very high mortality and disability rates. Despite intensive studies, molecular mechanisms underlying the pathophysiology of IA formation, growth, and rupture remain poorly understood.

Clinical Relevance of Changes in Peripheral Blood Cells After Intracranial Aneurysm Rupture.

Background: The rupture of an intracranial aneurysm (IA) causes a systemic response that involves an immune/inflammatory reaction. We sought to characterize the systemic response to IA rupture.

Methods: We included 19 patients in the acute phase of IA rupture and 20 control subjects.

Opposite regulation of piRNAs, rRNAs and miRNAs in the blood after subarachnoid hemorrhage.

Multiple classes of small RNAs (sRNAs) are expressed in the blood and are involved in the regulation of pivotal cellular processes. We aimed to elucidate the expression patterns and functional roles of sRNAs in the systemic response to intracranial aneurysm (IA) rupture. We used next-generation sequencing to analyze the expression of sRNAs in patients in the acute phase of IA rupture (first 72 h), in the chronic phase (3-15 months), and controls.

Recanalization of Embolized Endovascular Intracranial Aneurysms and Changes in the Blood Viscosity: A Pilot Study.

BACKGROUND The purpose of our research was to evaluate the relationships between blood viscosity and recanalization of coiled intracranial aneurysms. MATERIAL AND METHODS The study included consecutives patients treated endovascularly by a team of experienced neurosurgeons and neuroradiologists due to brain aneurysm. A total of 50 patients (the average age was 57.

Inflammatory Responses Induced by the Rupture of Intracranial Aneurysms Are Modulated by miRNAs.

Influence of an intracranial aneurysm (IA) rupture on the expression of miRNAs and the potential significance of the resulting changes remains poorly understood. We aimed to characterize the response to the IA rupture through the analysis of miRNAs in peripheral blood cells. Expression of small RNAs was investigated using deep transcriptome sequencing in patients in the acute phase of an IA rupture (first 72 h), in the chronic phase (3-15 months), and controls.

Systemic response to rupture of intracranial aneurysms involves expression of specific gene isoforms.

Background: Rupture of an intracranial aneurysm (IA) causes a systemic response that involves an immune/inflammatory reaction. Our previous study revealed a downregulation of genes related to T lymphocytes and an upregulation of genes related to monocytes and neutrophils after IA rupture. It remains unknown whether that resulted from alterations in transcription or cell count.

[Management of multiple myeloma-related bone disease].

Multiple myeloma is still incurable malignant neoplasm of plasma cells, which is characterized by the presence of osteolytic bone disease, the latter resulting from increased osteoclast function accompanied by decreased osteoblast activity. Myeloma bone disease is associated with the risk of skeletal events, such as pathologic fractures, spinal cord compression, or a need of palliative bone treatment or surgery, and may be related to decreased survival. In this review article, the results of the studies analyzing treatment options for myeloma bone disease and its complications are summarized.

Assessment of the haemostatic system in patients surgically treated for ruptured cerebral aneurysm.

Background And Purpose: The aim of the study was to evaluate selected markers of thrombin generation and subsequent fibrinolysis in patients with aneurysmal subarachnoid haemorrhage (SAH) and to assess the relationship between thrombin generation/fibrinolysis and clinical course and outcome.

Material And Methods: This prospective study included 72 patients after aneurysmal SAH who underwent surgery within 72 hours after onset of symptoms. The results were compared with 84 control patients without SAH.

[Pneumocephalus after shunt in a patient with hydrocephalus. A case report and review of the literature].

Pneumocephalus in hydrocephalic shunted patients is very rare. So far only 46 cases have been described in the literature. A case of pneumocephalus in a patient with shunted hydrocephalus, and the diagnostic and therapeutic problems were described.