Analysis of the Influence of Hormone Replacement Therapy on Osteocalcin Gene Expression in Postmenopausal Women.

Background: Osteocalcin (OC) contributes to the process of bone mineralization. Present study was designed to investigate the changes in OC gene expression of postmenopausal women treated with hormone replacement therapy (HRT). Study was also designed to evaluate OC gene expression in cells which are not part of connective tissue.

Analysis of the influence of parenteral cancer chemotherapy on the health condition of oral mucosa.

Aim Of The Study: The present study was aimed at estimating the prevalence of oral complications in cancer patients receiving chemotherapy.

Material And Methods: The study was conducted on a group of 58 patients treated with chemotherapy (study group). The control group consisted of 30 healthy patients.

Influence of hormone replacement therapy on osteoprotegerin and receptor activator of nuclear factor kappa-B ligand concentrations in menopausal women.

The study was designed to compare the levels of the receptor activator of nuclear factor kappa-B ligand (RANKL) and osteoprotegerin (OPG) in the serum and saliva of menopausal women and verify whether there is a correlation between concentrations of these cytokines and bone mineral density (BMD) of the femur and mandible. Blood and saliva samples were collected from a group of 60 women during menopause--30 untreated (control group) and 30 treated with hormone replacement therapy (HRT) (research group). Densitometry was conducted on the femoral bone and mandible.

IL-1α and IL-1β levels in blood serum and saliva of menopausal women.

Objective: The aim of this study was to examine the level of IL-1α and IL-1β in serum and saliva of postmenopausal women.

Design: The study was designed to verify the possibility of using the salivary concentration of interleukin 1 as a marker in the diagnosis of osteoporosis.

Materials And Methods: The study involved a group of 60 women during menopause-30 untreated and 30 treated with hormone replacement therapy.

Analysis of the influence of hormone replacement therapy on TNF-alpha serum levels in menopausal women.

Objective: The aim of the study was to investigate and compare levels of TNF-α in serum of menopausal women treated and not treated with hormone replacement therapy (HRT).

Design: The study was designed to verify whether there is a correlation between the concentrations of this cytokine and bone mineral density (BMD).

Material/methods: The study was carried out on a group of 60 women during menopause - 30 untreated (control group) and 30 treated with HRT (study group).