Evaluation of polymorphisms and expression of , and genes in vitiligo patients.

Introduction: Vitiligo is a pigmentary disorder associated with a selective loss of melanocytes in the skin, its appendages and mucous membranes.

Aim: The aim of the study was to evaluate the association between the rs2476601 polymorphism of the gene, the rs2670660 and rs6502867 polymorphisms of the gene and the rs1847134 and rs1393350 polymorphisms of the gene and vitiligo. Another aim was to compare the gene expression in lesional and symmetrically non-lesional skin of vitiligo patients and healthy controls.