Publications by authors named "Rafaella Siang"
Article Synopsis
- The study focuses on distinguishing near-field (NF) and far-field (FF) electrograms (EGMs) to better identify critical areas for treating ventricular tachycardia (VT) during ablation procedures, using a new algorithm for EGM analysis.
- A multicenter study involving 30 patients was conducted, analyzing a massive dataset of EGMs to compare peak frequencies (PF) in different heart rhythms, revealing significant differences that could aid in pinpointing problematic heart circuits.
- Results indicated that a low-voltage area PF threshold of ≥200 Hz is effective for identifying VT isthmus, with findings suggesting that chronic amiodarone treatment can lower these PF values, potentially impacting treatment outcomes.
Fibrosis is a potentially debilitating disease with high morbidity rates. It is estimated that half of all deaths that occur in the USA are attributed to fibrotic disorders. Fibrotic disorders are characterized primarily by disruption in the extracellular matrix deposition and breakdown equilibrium, leading to the accumulation of excessive amounts of extracellular matrix.
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