Publications by authors named "Rafaella P L Magnago"
The growth of the elderly population is a worldwide phenomenon and it is associated with chronic diseases, including dementia. In this scenario, the present study aimed to evaluate a possible association of estrogen receptor α polymorphisms with dementia in a Brazilian cohort. The subject sample was divided into two groups, control ( = 105) and case ( = 73), according to analysis of two predictive dementia tests (MMSE and CDR).
View Article and Find Full Text PDFOsteoporosis is one of the major diseases that affects mostly postmenopausal women. Despite being a multifactorial disease, some genes have been shown to play an important role in osteoporosis. Bone mineral density (BMD) is still largely used to diagnose it, although many other biomarkers are used to better follow the disease onset.
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- Tributyltin chloride (TBT) is a harmful pollutant used in antifouling paints that disrupts endocrine function and affects renal health.
- In a study where female rats were exposed to TBT, significant renal issues were found, including decreased glomerular filtration rates and increased protein levels in urine.
- The study also noted inflammation, collagen buildup, reduced estrogen levels, and disrupted cellular balance, indicating that TBT negatively impacts kidney function and structure.