Publications by authors named "Rafaela da Cunha Pirolla"
The use of hypoglycemic drugs in Parkinson's disease: An updated meta-analysis of randomized controlled trials.
Milene Vitória Sampaio Sobral Victor Gonçalves Soares João Lucas de Magalhães Leal Moreira Livia Kneipp Rodrigues Paula Rocha Rafaela da Cunha Pirolla
Parkinsonism Relat Disord
January 2025
Introduction: Recent studies have demonstrated an association between hypoglycemic medications and neuroprotective action in neurodegenerative diseases, such as Parkinson's disease (PD). Therefore, in this meta-analysis, our objective was to evaluate the efficacy of these medications, compared to placebo, as disease-modifying therapy in patients with PD.
Methods: We systematically searched PubMed, Embase, and Cochrane for studies comparing the use of hypoglycemic drugs and placebo in patients with PD.
Efficacy and Safety of Inhibitors of the Proximal Pathway of the Complement System in Paroxysmal Nocturnal Hemoglobinuria: A Meta-analysis of Randomized Controlled Trials.
Milene Vitória Sampaio Sobral Isac Ribeiro Moulaz Victor Gonçalves Soares Rafaela da Cunha Pirolla Lucas Cael Azevedo Ramos Bendaham
Am J Ther
October 2024
Article Synopsis
- A systematic review compared the effectiveness and safety of oral versus topical minoxidil in treating androgenetic alopecia, analyzing data from four randomized clinical trials involving 279 patients.
- The study found no significant differences between the two forms of minoxidil regarding hair density and diameter, suggesting both treatments are similarly effective.
- However, oral minoxidil resulted in a higher occurrence of hypertrichosis (excess hair growth), while the incidence of hypotension was not significantly different between the two groups.