Pacemaker implantation in familial amyloid polyneuropathy: when and for whom?

Background: Despite the important role of cardiac pacing in preventing syncope and sudden cardiac death in familial amyloid polyneuropathy (FAP), we lack clear guidelines as to the ideal timing and indications for permanent pacemaker implantation.

Purpose: The purpose of this study was to evaluate the ideal timing for pacemaker implantation in FAP patients submitted to liver transplantation.

Methods: Retrospective study of 258 FAP patients submitted to liver transplantation between 1992 and 2012.