Publications by authors named "Rafaela Luiza Klein"

Glässer's disease is one of the main diseases affecting young piglets, particularly during the nursery phase, that can significantly impact pork production. Vaccination of sows has the potential to prevent Glaesserella parasuis infection during the first weeks of life that is to a substantial degree due to the transfer of maternal derived antibodies (MDA) in colostrum. In this study we compare the antibody response to two vaccines administered to pregnant sows.

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Hepatitis E virus (HEV) is worldwide distributed and might cause acute or chronic hepatitis mainly in immunocompromised individuals. In previous studies we found a high prevalence of antibodies to HEV within blood donors in south Brazil and also within backyard-raised pigs. Here, we aimed to investigate the prevalence of anti-HEV antibody and HEV RNA within the general population from three major municipalities (Caxias do Sul, Passo Fundo and Santa Maria) in south Brazil.

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Synopsis of recent research by authors named "Rafaela Luiza Klein"

  • - Rafaela Luiza Klein's research primarily focuses on veterinary microbiology, with significant attention to the impact of vaccines on disease prevention in livestock, particularly swine.
  • - In her study on a TbpB-based vaccine, she found it to be safe for pregnant sows and effective in inducing high titers of maternal derived antibodies that significantly reduce Glaesserella parasuis colonization in piglets, thereby mitigating Glässer's disease.
  • - Additionally, Klein investigated the prevalence of hepatitis E virus antibodies in South Brazil, revealing an unusually high prevalence in both the general population and backyard-raised pigs, underscoring public health concerns related to zoonotic infections.