Publications by authors named "Rafael de Souza Silva"

Article Synopsis
  • Paracoccidioidomycosis (PCM) is a common fungal infection in Latin America, caused by a specific fungus, which enters the body through inhalation and changes its form.
  • The study focused on aspartyl proteases, essential enzymes that help the fungus invade the host and evade the immune response.
  • Researchers found that these proteases are influenced by environmental conditions, such as pH and nutrient availability, and their activity plays a critical role in the fungus's growth and relationship with the host.
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The aim of the present study was to investigate the impact of the activation of estrogen receptors on expression and localization of N-cadherin, E-cadherin and non-phosphorylated β-catenin in androgen-independent prostate cancer cells (PC-3 and DU-145) and in human post pubertal prostate epithelial cells (PNT1A). Expression of N-cadherin was detected in PNT1A and PC-3 cells, but not in DU-145 cells. E-cadherin was detected only in DU-145 cells and β-catenin was detected in all cells studied.

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