Publications by authors named "Rafael Salvador Izquierdo"
Urolithiasis is a common disease with increasing prevalence worldwide and a lifetimeestimated recurrence risk of over 50%. Imaging techniques play a critical role in the initial diagnosis, follow-up and urological management of urinary tract stone disease. The are many useful tools for diagnosing urolithiasis, including conventional plain radiography, intravenous urography, ultrasonography, computed tomography and magnetic resonance imaging.
View Article and Find Full Text PDFRecent advances in treatment of metastatic renal cell carcinoma (RCC), such as new molecular therapies that use novel antiangiogenic agents, have led to revision of the most frequently used guideline to evaluate tumor response to therapy: Response Evaluation Criteria in Solid Tumors (RECIST 1.1). Assessment of the response of metastatic RCC to therapy has traditionally been based on changes in target lesion size.
View Article and Find Full Text PDFRetroperitoneal fibrosis (RPF) encompasses a range of diseases characterized by proliferation of aberrant fibroinflammatory tissue, which usually surrounds the infrarenal portion of the abdominal aorta, inferior vena cava, and iliac vessels. This process may extend to neighboring structures, frequently entrapping and obstructing the ureters and eventually leading to renal failure. The idiopathic form of RPF accounts for more than two-thirds of cases; the rest are secondary to factors such as drug use, malignancies, or infections.
View Article and Find Full Text PDFArticle Synopsis
- - A study was conducted to investigate if kidney stones (nephrolithiasis) cause changes in the density of renal papillae, comparing a stone-forming group (SFG) with a healthy control group (CG).
- - The results indicated that the papillae density in the SFG was significantly higher (43.9 HU) compared to the CG (33.9 HU), while no notable difference was found between the affected and unaffected sides in the SFG.
- - The findings support the theory of calcium deposits in the renal papillae, with a high accuracy rate in distinguishing between the two groups based on papillae density measurements (area under the curve of 0.91).
Objectives: To determine if calcium deposits in the papillae can be identified by unenhanced computed tomography (uCT) even before renal stones develop.
Methods: A retrospective review of 413 patients with calculi identified 31 patients (stone-forming group) with a history of urinary tract calculi with a calculus demonstrated by uCT and a stone-free uCT before calculi had developed. The control group (n = 31) was composed of live kidney donors with no history of calculi and a stone-free uCT.