Prediabetes, undiagnosed T2D, insulin resistance and metabolic syndrome in Guanajuato, Mexico.

Objective: To evaluate the prevalence of prediabetes (PD), undiagnosed type 2 diabetes (T2D), metabolic syndrome (MetS), and insulin resistance (IR) as well as related risk factors in Mexican population from Guanajuato, Mexico.

Materials And Methods: We performed a cross-sectional study in the Mexican population from León, Guanajuato, Mexico. A clinical and metabolic evaluation was performed with an oral glucose test (OGTT); PD, undiagnosed T2D, MetS, and IR were identified according to international guidelines.

Pancreatic β-cell dysfunction in normoglycemic patients and risk factors.

Aims: To evaluate pancreatic β-cell function (βf) in patients with normoglycemia (NG) and normal glucose tolerance (NGT) and related risk factors.

Methods: An observational and comparative study in 527 patients with NG and NGT that were divided by quartiles of βf according to the disposition index derived from OGTT. Anthropometrical, clinical, nutritional, and biochemical variables were measured and associated with βf.