Publications by authors named "Rafael Rodrigues Lima"

This study aimed to evaluate the effects of excessive and episodic consumption of ethanol (EtOH, a high-intensity drinking manner) on induced apical periodontitis in rats. Thirty-two animals were divided into the following four groups: control, EtOH, apical periodontitis, and EtOH + apical periodontitis. Ethanol exposure (3 g/kg 20 % w/v EtOH) was performed by orogastric gavage for 3 consecutive days, followed by 4 days of withdrawal for 4 weeks.

View Article and Find Full Text PDF

This study aimed to evaluate the level of oral health knowledge among teachers in a city of the Brazilian Amazon region (Belem, Pará) and explore the association between teachers' knowledge and their proposed actions in the event of dental trauma accidents within the school environment. The descriptive cross-sectional study involved 170 elementary teachers from public schools in the Metropolitan Region of Belem, Para State, Brazil. A self-administered questionnaire with multiple-choice questions was utilized to assess teachers' oral health knowledge across various domains.

View Article and Find Full Text PDF

Lead poisoning is a global public health concern. Maternal exposure during intrauterine and lactational periods can present a higher susceptibility of harm to the offspring. Thus, pregnant female Wistar rats (Rattus norvegicus) were randomly divided in two experimental groups: control group and Lead group.

View Article and Find Full Text PDF

Background: To compare, through a systematic literature review, the cost-effectiveness ratio of home care compared to hospital care for following up patients with chronic obstructive pulmonary disease (COPD).

Methods: This review was registered in PROSPERO, and the bibliographic search was performed in six primary databases [MedLine (via PubMed), Scopus, LILACS, SciELO, Web of Science, and Embase], two dedicated databases for economic studies (NHS Economic Evaluation Database (NHS EED) and Cost-Effectiveness Analysis (CEA) Registry), and two databases for partially searching the "gray literature" (DansEasy and ProQuest). This review only included studies that compared home and hospital care for patients diagnosed with COPD, regardless of publication year or language.

View Article and Find Full Text PDF

This study aimed to investigate the impact of minocycline on the alveolar bone in experimental periodontitis in rats. Thirty Wistar rats were randomly assigned to three groups: control without periodontitis; experimental periodontitis induced by ligature; experimental periodontitis + intraperitoneal administration minocycline for seven days. Ligatures remained in place in both periodontitis groups for 14 days.

View Article and Find Full Text PDF

The hypothalamus-pituitary-adrenal axis (HPA axis) and the sympathetic-adrenal-medullary system (SAM system), two neuroendocrine systems associated with the stress response, have often been implicated to modulate decision-making in various domains. This systematic review summarizes the scientific evidence on the effects of pharmacological HPA axis and SAM system modulation on decision-making. We found 6375 references, of which 17 studies fulfilled our inclusion criteria.

View Article and Find Full Text PDF

Amelogenesis, the intricate process governing enamel formation, is susceptible to a range of genetic, systemic, and environmental influences, resulting in distinct developmental defects of enamel (DDE), such as molar incisor hypomineralisation (MIH), enamel hypoplasia, dental fluorosis, and amelogenesis imperfecta (AI). This chapter aims to provide a comprehensive overview of amelogenesis and DDE, establishing correlations between histopathological findings and clinical manifestations. MIH, a qualitative enamel defect, occurs during the mineralisation and maturation phases, affecting first permanent molars and eventually incisors.

View Article and Find Full Text PDF

Maintenance and improvement of an individual's overall well-being require a multidisciplinary approach that encompasses everything from oral health care to regular physical exercise. The notion that poor oral health can influence general health and athletic performance has sparked an interest in this relationship. This study offers an overview of relevant research and a knowledge map,and discusses publication metrics and key topics concerning the relationship between physical activity or exercise and oral diseases.

View Article and Find Full Text PDF

Volatile oils or essential oils (EOs) were extracted from three samples (labeled as A, B, and C) in September 2018 and February 2019; the extraction process involved hydrodistillation of the leaves. The chemical compositions of the EOs were analyzed using gas chromatography-mass spectrometry (GC/MS). The volatile components were identified by comparing their retention indices and mass spectra with standard substances documented in the literature (ADAMS).

View Article and Find Full Text PDF

Linalool-rich Rosewood oil (Aniba rosaeodora Ducke) is a natural compound widely used in perfumery industry. Evidence suggests that linalool exerts antidepressant and anxiolytic effects. Conversely, ethanol binge drinking (i.

View Article and Find Full Text PDF
Article Synopsis
  • * Rats treated with TC showed increased testosterone levels in both plasma and saliva but did not experience changes in salivary flow, pH, or buffering capacity; however, certain proteins and minerals in saliva decreased.
  • * The results indicate that TC may harm the parotid and submandibular glands, which could pose risks to oral and overall health for individuals who misuse anabolic steroids.
View Article and Find Full Text PDF

The objective of this study is to investigate the effects of a moderate intensity physical training protocol, on alveolar bone morphology of rats submitted to ligature-induced periodontitis. Twenty-eight male Wistar rats were divided into four groups, considering the presence/absence of periodontitis and presence/absence of training. The training protocol was performed on a treadmill, 30 min/day, 5 days a week, for 4 weeks.

View Article and Find Full Text PDF
Article Synopsis
  • This systematic review investigated the link between apical periodontitis (a dental condition) and systemic biomarkers in adults, using established research protocols like PRISMA.
  • The study evaluated 656 initial articles, ultimately including 17 after applying specific eligibility criteria, and assessed their methodological quality, revealing varying levels of bias among them.
  • Findings indicated a significant association between apical periodontitis and specific inflammatory biomarkers, such as interleukins (IL-1, IL-2, IL-6) and immunoglobulins (IgG, IgM), primarily measured in blood plasma and saliva.
View Article and Find Full Text PDF

Objective: To overview the literature to answer the following question: "What is the performance of different therapies on wound healing and postoperative discomfort after palatal ASTG removal?"

Methods: SRs that evaluated the wound healing (WH), postoperative pain, bleeding, and analgesic consumption of patients submitted to de-epithelialized/free gingival grafts (FGG) or subepithelial connective tissue grafts (SCTG) removed from the palate were included. The searches were conducted on six white and two gray databases up to December 2023. Methodological quality was evaluated through AMSTAR 2.

View Article and Find Full Text PDF

The açai juice contains high concentrations of phenolic compounds, including cyanidin-3-glucoside and others flavonoids. The aim of this study was to evaluate the impact of açai supplementation on healthy mandibular alveolar bone in male albino rats of the Wistar strain. 24 rats were divided into 3 groups, in which one group received a daily dose of saline solution and the other two groups were treated with daily doses of clarified açai juice for 14 or 28 days.

View Article and Find Full Text PDF
Article Synopsis
  • Myofibromas (MF) and myofibromatosis (MFT) are rare benign tumors found in the oral and maxillofacial regions, primarily affecting men and presenting as painless nodules.
  • A systematic review of 169 cases revealed that MF typically appears in the gingiva for soft tissue and in the posterior mandible for intra-osseous lesions, with MFT noted for its well-circumscribed spindle cell masses.
  • Surgical excision is the main treatment, and the overall prognosis is favorable, with low rates of recurrence.
View Article and Find Full Text PDF

The emergence of antimicrobial resistance among biofilm forming pathogens aimed to search for the efficient and novel alternative strategies. Metallic nanoparticles have drawn a considerable attention because of their significant applications in various fields. Numerous methods are developed for the generation of these nanoparticles however, mycogenic (fungal-mediated) synthesis is attractive due to high yields, easier handling, eco-friendly and being energy efficient when compared with conventional physico-chemical methods.

View Article and Find Full Text PDF

We aimed to investigate the effectiveness of physical training as a protective strategy to mitigate alveolar bone damage and blood antioxidant defense caused by ethanol (EtOH) consumption in a binge-drinking pattern. Male Wistar rats aged approximately 90 days were divided into four groups: control, training, EtOH, and training + EtOH. The physical training protocol was conducted on a treadmill for four consecutive weeks, while the animals in the EtOH group were administered EtOH via orogastric gavage for three consecutive days each week, following the binge drink pattern.

View Article and Find Full Text PDF
Article Synopsis
  • Numerous studies have investigated the effects of fluoride (F) on various systems, especially its interaction with the thyroid, but a clear consensus is still lacking.
  • This systematic review aimed to collate evidence regarding the impact of fluoride levels in drinking water on thyroid function, focusing on studies recognized by the World Health Organization.
  • Out of 3,568 studies, only seven met the criteria, with five indicating that high fluoride exposure may harm thyroid function; however, all studies had significant methodological issues leading to low confidence in the findings.
View Article and Find Full Text PDF
Article Synopsis
  • - Mercury is a serious environmental and public health threat due to its toxic effects, and this study focused on assessing its impacts on human health through experimental research.
  • - Using bibliometric analysis of articles published between 1965 and 2021, the study identified key trends, including that the USA contributed 38% of the research and highlighted Clarkson TW as a leading author in the field.
  • - The findings emphasized the significant neurodevelopmental risks associated with mercury exposure, particularly methylmercury, and identified gaps in current knowledge that could inform future research and policy development.
View Article and Find Full Text PDF
Article Synopsis
  • - Apical periodontitis (AP) is an inflammatory condition affecting the tooth canal and surrounding tissues, which can lead to systemic health issues.
  • - The study examined how aerobic physical training (PT) influences both the alveolar bone and inflammatory responses in cases with and without AP.
  • - Results showed that PT reduced inflammation and bone damage in AP-affected areas, suggesting it can be an effective strategy for patients undergoing dental treatment.
View Article and Find Full Text PDF

Background: Local anesthetic puncture is often related to the experience of pain. This study aimed to systematically analyze the literature on changes in pain perception during the anesthetic puncture of dental local anesthesia after Photobiomodulation Therapy (PBMT).

Material And Methods: An electronic search was performed in eight primary databases (Embase, LILACS, BBO, LIVIVO, MedLine via PubMed, SciELO, Scopus, and Web of Science) and three additional ones (EASY, Google Scholar, and OATD) to partially capture the "gray literature".

View Article and Find Full Text PDF

The use of natural products such as essential oils has been suggested due to their promising pharmacological effects and economic viability. This study aimed to determine hydrogenic potential (pH), titratable acidity (TA), and ion concentrations of five solutions containing essential oils (EO), when used as a EO-containing solutions, and evaluate ion concentrations, enamel surface loss, and morphology alterations in enamel. The pH, TA, calcium (Ca), potassium (K), and sodium (Na) concentrations of five EO-containing solutions were measured.

View Article and Find Full Text PDF

The use of bleaching agents to remove stains is one of the main dental procedures to improve the aesthetics of teeth. This review presents the main agents used for tooth whitening, existing clinical protocols, and the structural changes that may occur through their use. The main bleaching agents consist of hydrogen peroxide and carbamide peroxide, which are used in bleaching techniques for vital teeth.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: