Protective effects of Yerba mate (IIex paraguariensis) on prostate cancer development.

Objectives: Prostate cancer (PCa) is the most common adenocarcinoma in men >50 y of age. It has a long latency period, which provides time for preventive strategies like incorporating healthy eating habits. Yerba mate (YM) intake has been associated with numerous health benefits.

[Association between consumption of yerba mate and lipid profile in overweight women].

Introduction: yerba mate is a traditional drink consumed in South America, produced from toasted leaves of Ilex paraguariensis. Several studies have demonstrated its lipid-lowering properties due to the presence of polyphenols and saponins. Objective: to analyze the effect of daily yerba mate consumption on the values of serum lipids and body composition in overweight women.

[Lipid - lowering effect of mate tea intake in dyslipidemic subjects].

Introduction: Mate is the national infusion of Argentina and its properties on human health have not been fully elucidated.

Objective: To evaluate changes in lipid profile in dyslipidemic patients supplemented with yerba mate.

Methods: 121 dyslipidemic subjects (total cholesterol (TC), LDL cholesterol (LDLC) cholesterol and / or triglycerides (TG) elevated) without lipid-lowering therapy, both sexes (74 women and 47 men) between 40 and 60 years old were studied.

[High intake of lycopene together with low intake of red meat increases the total antioxidant status].

The body's antioxidant systems are able to remove free radicals, thus protecting the body from the damage they may cause. They can be estimated, as a whole, through the determination of total antioxidant status (TAS). This biomarker can be modulated by dietary factors through the incorporation of substances with antioxidant or prooxidant properties.

Leptin increases prostate cancer aggressiveness.

Recent studies indicate that adipose tissue and adipocytokines might affect the development of prostate cancer (PCa). Leptin would have a stimulating effect on prostate cancer cells by inducing promotion and progression, whereas adiponectin would have a protective effect. The aim of this study was to determine the relation between body composition, leptin, and adiponectin levels with the prevalence and aggressiveness of PCa in men of Mendoza, Argentina.

Obesity modifies prostatic specific antigen in men over 45 years.

Objectives: To determine whether lower serum prostate-specific antigen (PSA) concentration in obese men is caused by plasma hemodilution and/or decreased serum testosterone levels.

Methods: A sample of 413 men, from 45 to 75 years old, were randomly selected for the study among those who participated in prostate cancer screening at 2 urban urology practices in Argentina and Puerto Rico. Weight, height, serum testosterone and total PSA concentration were determined.

[Body mass index and diet affect prostate cancer development].

Introduction: Prostate cancer (CaP) is one of the most important causes of morbidity and mortality in the world. There is evidence that obesity and inadequate eating habits may promote CaP development.

Objective: To analyze and compare the body mass index (BMI) and the food intake, especially fats and antioxidants, among subjects with CaP and those free of disease as a control group.

[Advances on the influence of adipose tissue on prostate cancer].

Unlabelled: Numerous studies have investigated the association between obesity and prostate cancer (CaP), although the results have not been concluding due to the great difficulty to evaluate the effects of obesity on the development of this type of tumor. The aim of this study was to carry out a comprehensive over-view of the existing evidence about the role of adipose tissue in the prostate carcinogenesis. Recent evidence suggests that androgens, leptin, IL-6, VEGF, insulin and IGF-1 may play a role in PC progression, while adiponectin and IGFBP-3 may act as "anti-prostatic cancer" adipokines.

[Influence of leptin and adiponectin on prostate cancer].

Background: Many studies have investigated the association between obesity, adipose tissue-derived factors (leptin and adiponectin) and prostate cancer (CaP) but the results are still inconsistent.

Methods: The aim of this study was to carry out a comprehensive review of the existing evidence about the role of leptin and adiponectin in prostate carcinogenesis and to provide an overview of it.

Results: Recent evidence suggests that leptin may play a rol in prostate cancer progression, while adiponectin may act as an "antiprostatic cancer" adipokine.

[Antioxidant power and cellular damage in prostate cancer].

Objectives: To determine and compare the antioxidant power, cellular damage by lipidic peroxidation, and membrane damage in normal patients and patients with prostate cancer, so determining the antitumoral capacity.

Methods: The study population included 19 patients with elevated total PSA, greater than 4 ng/ml, with a minimum of 10 ultrasound guided transrectal biopsies, and 10 normal subjects as control group. In all cases, medical history, rectal digital examination, PSA determination and routine analyses were performed in addition to spectrophotometric tests to measure the antioxidant power.