Publications by authors named "Rafael Garrido-Pena"

Human culture, biology, and health were shaped dramatically by the onset of agriculture ∼12,000 y B.P. This shift is hypothesized to have resulted in increased individual fitness and population growth as evidenced by archaeological and population genomic data alongside a decline in physiological health as inferred from skeletal remains.

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Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene.

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Sheep remains constitute the main archaeozoological evidence for the presence of Early Neolithic human groups in the highlands of the Southern Pyrenees but understanding the role of herding activities in the Neolithisation process of this mountain ecosystem calls for the analysis of large and well-dated faunal assemblages. Cova de Els Trocs (Bisaurri, Huesca, Spain), a cave located at 1564 m a.s.

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Violence seems deeply rooted in human nature and an endemic potential for such is today frequently associated with differing ethnic, religious or socio-economic backgrounds. Ethnic nepotism is believed to be one of the main causes of inter-group violence in multi-ethnic societies. At the site of Els Trocs in the Spanish Pyrenees, rivalling groups of either migrating early farmers or farmers and indigenous hunter-gatherers collided violently around 5300 BCE.

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Article Synopsis
  • The Iberian Peninsula served as a key area for studying human population movements during prehistoric times, particularly during the Last Glacial Maximum (LGM), acting as a refuge for hunter-gatherers who later contributed to the repopulation of northern areas.
  • Recent research revealed that the genetic makeup of Iberian hunter-gatherers (HGs) includes ancestral ties to both the Villabruna individual from Italy and Magdalenian-related groups, indicating a complex ancestry in the region.
  • New genomic data from Iberian Early and Middle Neolithic individuals support the idea that as farming expanded into the region, there was significant mixing with the local hunter-gatherer populations, preserving the dual genetic legacy.
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We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect of the Iberian Peninsula. We document high genetic substructure between northwestern and southeastern hunter-gatherers before the spread of farming. We reveal sporadic contacts between Iberia and North Africa by ~2500 BCE and, by ~2000 BCE, the replacement of 40% of Iberia's ancestry and nearly 100% of its Y-chromosomes by people with Steppe ancestry.

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From around 2750 to 2500 bc, Bell Beaker pottery became widespread across western and central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled its expansion are a matter of long-standing debate, and there is support for both cultural diffusion and migration having a role in this process. Here we present genome-wide data from 400 Neolithic, Copper Age and Bronze Age Europeans, including 226 individuals associated with Beaker-complex artefacts.

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Article Synopsis
  • Agriculture arrived in the Iberian Peninsula around 5700 BCE, marking a shift in lifestyle from hunter-gatherers to farming communities.
  • This study analyzes the mitochondrial DNA of 213 individuals across various regions of Iberia from the Neolithic to the Early Bronze Age, contributing to a comprehensive understanding of prehistoric populations.
  • The findings indicate a notable genetic continuity in the Early Neolithic lineages, with a higher presence of hunter-gatherer genes in Iberia compared to other parts of Europe, suggesting a unique population history for the region.
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The analysis of the human remains from the megalithic tomb at Alto de Reinoso represents the widest integrative study of a Neolithic collective burial in Spain. Combining archaeology, osteology, molecular genetics and stable isotope analysis (87Sr/86Sr, δ15N, δ13C) it provides a wealth of information on the minimum number of individuals, age, sex, body height, pathologies, mitochondrial DNA profiles, kinship relations, mobility, and diet. The grave was in use for approximately one hundred years around 3700 cal BC, thus dating from the Late Neolithic of the Iberian chronology.

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Article Synopsis
  • Researchers analyzed ancient DNA from 69 Europeans dating back 8,000 to 3,000 years using advanced techniques that reduced sequencing time significantly, enabling the study of more individuals.
  • They discovered that during the Neolithic period, diverse populations of early farmers emerged in Western Europe while Eastern Europe maintained a distinct hunter-gatherer population with ties to ancient Siberians.
  • The study also highlighted a major migration event around 4,500 years ago, where the Corded Ware people from Germany mixed heavily with steppe herders from the east, contributing to modern European ancestry and supporting the theory of a steppe origin for some Indo-European languages.
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