Volcano transition in populations of phase oscillators with random nonreciprocal interactions.

Populations of heterogeneous phase oscillators with frustrated random interactions exhibit a quasiglassy state in which the distribution of local fields is volcanoshaped. In a recent work [Phys. Rev.

Randomized phase II trial of FOLFIRI-panitumumab compared with FOLFIRI alone in patients with RAS wild-type circulating tumor DNA metastatic colorectal cancer beyond progression to first-line FOLFOX-panitumumab: the BEYOND study (GEMCAD 17-01).

Purpose: Panitumumab plus FOLFOX (P-FOLFOX) is standard first-line treatment for RAS wild-type (WT) metastatic colorectal cancer. The value of panitumumab rechallenge is currently unknown. We assessed addition of panitumumab to FOLFIRI (P-FOLFIRI) beyond progression to P-FOLFOX in patients with no RAS mutations in liquid biopsy (LB).

Comment on "The Winfree model with non-infinitesimal phase-response curve: Ott-Antonsen theory" [Chaos 30, 073139 (2020)].

In a recent paper [Chaos 30, 073139 (2020)], we analyzed an extension of the Winfree model with nonlinear interactions. The nonlinear coupling function Q was mistakenly identified with the non-infinitesimal phase-response curve (PRC). Here, we assess to what extent Q and the actual PRC differ in practice.

Variational approach to KPZ: Fluctuation theorems and large deviation function for entropy production.

Motivated by the time behavior of the functional arising in the variational approach to the Kardar-Parisi-Zhang (KPZ) equation, and in order to study fluctuation theorems in such a system, we have adapted a path-integral scheme that adequately fits to this kind of study dealing with unstable systems. As the KPZ system has no stationary probability distribution, we show how to proceed for obtaining detailed as well as integral fluctuation theorems. This path-integral methodology, together with the variational approach, in addition to allowing analyze fluctuation theorems, can be exploited to determine a large deviation function for entropy production.

The Winfree model with non-infinitesimal phase-response curve: Ott-Antonsen theory.

A novel generalization of the Winfree model of globally coupled phase oscillators, representing phase reduction under finite coupling, is studied analytically. We consider interactions through a non-infinitesimal (or finite) phase-response curve (PRC), in contrast to the infinitesimal PRC of the original model. For a family of non-infinitesimal PRCs, the global dynamics is captured by one complex-valued ordinary differential equation resorting to the Ott-Antonsen ansatz.

Synchronization scenarios in the Winfree model of coupled oscillators.

Fifty years ago Arthur Winfree proposed a deeply influential mean-field model for the collective synchronization of large populations of phase oscillators. Here we provide a detailed analysis of the model for some special, analytically tractable cases. Adopting the thermodynamic limit, we derive an ordinary differential equation that exactly describes the temporal evolution of the macroscopic variables in the Ott-Antonsen invariant manifold.

Synchronizing spatio-temporal chaos with imperfect models: a stochastic surface growth picture.

We study the synchronization of two spatially extended dynamical systems where the models have imperfections. We show that the synchronization error across space can be visualized as a rough surface governed by the Kardar-Parisi-Zhang equation with both upper and lower bounding walls corresponding to nonlinearities and model discrepancies, respectively. Two types of model imperfections are considered: parameter mismatch and unresolved fast scales, finding in both cases the same qualitative results.

Pseudospectral versus finite-difference schemes in the numerical integration of stochastic models of surface growth.

We present a comparison between finite differences schemes and a pseudospectral method applied to the numerical integration of stochastic partial differential equations that model surface growth. We have studied, in 1+1 dimensions, the Kardar, Parisi, and Zhang model (KPZ) and the Lai, Das Sarma, and Villain model (LDV). The pseudospectral method appears to be the most stable for a given time step for both models.

Processing of ultrasonic array signals for characterizing defects. Part II: experimental work.

This is Part II of the two-part paper aimed at integrating the numerical synthesis and experimental investigation of the ultrasonic wave propagation model for quantitative nondestructive evaluation. The first part of the paper focused on synthesizing and predicting measured signals using the boundary element method and the deconvolution technique based on the comparison between the signals obtained from defective and undamaged (reference) specimens. In the second part, we present an inversion technique which allows us to obtain the position and size of the defect.

Processing of ultrasonic array signals for characterizing defects. Part I: signal synthesis.

This work presents a novel procedure to characterize damage using an array of ultrasonic measurements in a generalized model-based inversion scheme, which integrates the complete information recorded from the measurements. In the past, we proposed some idealized nondestructive evaluation test methods with emphasis on the numerical results, but it is necessary to develop the techniques in greater detail in order to apply the techniques to real conditions. Our detection principle is based on the measurement and inversion of frequency-domain data combined with a reduced set of output parameters.

Scaling of local slopes, conservation laws, and anomalous roughening in surface growth.

We argue that symmetries and conservation laws greatly restrict the form of the terms entering the long wavelength description of growth models exhibiting anomalous roughening. This is exploited to show by dynamic renormalization group arguments that intrinsic anomalous roughening cannot occur in local growth models. However, some conserved dynamics may display superroughening if a given type of term is present.

Design of ultrasonic wedge transducer.

Cones and wedges inserted between an ultrasonic transducer and the specimen provide the transducer (circular or rectangular shape) with enhanced capability for point or line contact with the specimen. Such an arrangement is useful in that the transducer can be used for transmitting to and receiving from a point (or line) source, and that it can eliminate the undesirable aperture effect that makes the transducer blind to waves traveling in certain directions and those of certain frequencies. In this paper, a comprehensive numerical analysis based on a wave propagation model is carried out for the study of characteristics and parameters of cones and wedges influencing their performance.