Antigenotoxic potential of the fermentation broth produced by RNC-D .

Evaluate the chemopreventive potential of the extract from RNC-D. Concentrations of RNC-D extract were tested in HepG2/C3A cells to assess their genotoxic (comet assay), mutagenic (micronucleus test) and antigenotoxic potential (comet assay) . 400 and 40 μg/ml concentrations induced DNA lesions, whereas the 4 μg/ml induced a desmutagenic effect.