Production of podophyllotoxin from roots and plantlets of Hyptis suaveolens cultivated in vitro.

Background: Hyptis suaveolens was an important source of food and medicines in pre-hispanic Mιxico and is actually used popularly to treat respiratory and skin diseases, fever, pain, and cramps, between other ailments. In 2008 the presence of podophyllotoxin (PTOX) was reported in this plant.

Objective: To establish in vitro cultures of H.