[Clinical implementation of non-invasive prenatal study for detecting aneuploidies by fetal DNA based on single nucleotide polymorphisms: two years in Mexico].

Background: Recent data have shown that non invasive prenatal test (NIPT) for the detection of fetal aneuploidies (chromosomes 13, 18, 21, X, Y, and triploidy) by cell free fetal DNA in maternal blood (cfDNA) is a clinical reality, with detection rates > 99% and false positive rates of 0.1%. Results that exceed the first trimester screening.

[Prevalence of chromosomal alterations in infertile patients studied in a clinic of assisted reproduction].

Background: Chromosomal abnormalities are a frequent cause of infertility. There is not consensus if should be included in the work-up of infertile couple.

Objective: to evaluate the prevalence of chromosomal abnormalities in our population of infertile couple and support the cytogenetic exam in the initial protocol.