Infectious crystalline keratopathy caused by Cladosporium sp. after penetrating keratoplasty: a case report.

Background: Infectious crystalline keratopathy is a rare, progressive infection characterized by the insidious progression of branches and crystalline corneal opacities with minimal or no inflammation. This case report describes the evolution of an infectious crystalline keratopathy caused by Cladosporium sp., which developed after tectonic keratoplasty in a patient with a history of ocular trauma.

A novel rat contact lens model for Fusarium keratitis.

Purpose: The aim of this study was to develop and characterize a new contact lens-associated fungal keratitis rat model and to assess the ability of non-invasive spectral-domain optical coherence tomography (SD-OCT) to detect pathological changes in vivo in fungal keratitis.

Methods: We used SD-OCT to image and measure the cornea of Sprague Dawley rats. Fusarium infection was initiated in the rat eye by fitting Fusarium solani-soaked contact lenses on the experimental eye, while the control animals received contact lenses soaked in sterile saline.

Fusarium keratitis in Brazil: genotyping, in vitro susceptibilities, and clinical outcomes.

Background: The purpose of this paper is to describe clinical characteristics and determine correlations between clinical outcomes and antifungal susceptibility among molecularly characterized ocular Fusarium isolates in Brazil.

Methods: Forty-one Fusarium isolates obtained from 41 eyes of 41 patients were retrieved from the ophthalmic microbiology laboratory at São Paulo Federal University and grown in pure culture. These isolates were genotyped and antifungal susceptibilities determined for each isolate using a broth microdilution method.

Fusarium keratitis: genotyping, in vitro susceptibility and clinical outcomes.

Purpose: To determine differences in the clinical characteristics and antifungal susceptibility patterns among molecularly characterized ocular Fusarium sp isolates.

Methods: Fifty-eight isolates of Fusarium sp obtained from 52 eyes of 52 patients were retrieved from the Ocular Microbiology Laboratory of the Bascom Palmer Eye Institute and grown in pure culture. These isolates were characterized based on DNA sequence analysis of the ITS1/2 and ribosomal deoxyribonucleic acid regions.

Clinical and microbiological characteristics of fungal keratitis in the United States, 2001-2007: a multicenter study.

Objective: To study the epidemiology, clinical observations, and microbiologic characteristics of fungal keratitis at tertiary eye care centers in the United States.

Design: Retrospective multicenter case series.

Participants: Fungal keratitis cases presenting to participating tertiary eye care centers.

Trends in fungal keratitis in the United States, 2001 to 2007.

Objective: Fungal keratitis is a serious ocular infection that is considered to be rare among contact lens wearers. The recent Fusarium keratitis outbreak raised questions regarding the background rate of Fusarium-related keratitis and other fungal keratitis in this population.

Design: Retrospective, multicenter case series.

Drug-resistant severe Acanthamoeba keratitis caused by rare T5 Acanthamoeba genotype.

Objective: To describe a case of severe and drug-resistant Acanthamoeba keratitis in a contact lens wearer caused by atypical T5 Acanthamoeba genotype (Acanthamoeba lenticulata).

Methods: Report of a case, Acanthamoeba DNA amplification and sequencing.

Results: A 61-year-old patient was referred to our clinic with a 2-week history of keratitis.

Utility of molecular sequence analysis of the ITS rRNA region for identification of Fusarium spp. from ocular sources.

Purpose: Fungal ocular infections cause significant ocular morbidity, particularly when diagnosis and treatment are delayed. Accurate morphologic identification of Fusarium spp. beyond the genus is time-consuming and insensitive.

[Influence of corneal astigmatism in final visual acuity after implantation of AcrySof ReSTOR: case report].

Currently, new types of intraocular lenses have been developed aiming to eliminate presbyopia and the use has become more popular. The authors report the case of a patient with bilateral cataract and corneal irregularities and astigmatism higher than 2D in the corneal topography, in which AcrySof ReSTOR intraocular lens was implanted in the left eye associated to relaxing limbal incisions trying to reduce corneal astigmatism. The near and distance postoperative visual acuity were worse than expected, with no improvement with refraction.