Extended criteria brain-dead organ donors: Prevalence and impact on the utilisation of livers for transplantation in Brazil.

Background: Despite its association with higher postoperative morbidity and mortality, the use of extended criteria donor (ECD) livers for transplantation has increased globally due to the high demand for the procedure.

Aim: To investigate the prevalence of ECD in donation after brain death (DBD) and its impact on organ acceptance for transplantation.

Methods: Retrospective analysis of DBD organ offers for liver transplantation between 2017 and 2020 in a high-volume transplant centre.

What is the role of heat shock protein in abdominal organ transplantation?

Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome.

Disposal of donor livers in Brazil: how to optimize their utilization rate in transplants?

Objective: To understand the professionals´ perception of the use of deceased donor liver for transplantation, the reasons to decline them, and propose strategies to increase their use safely.

Methods: This is a cross-sectional, descriptive qualitative-quantitative study. Professionals working with liver transplantation answered a self-administered, structured, and electronic questionnaire comprising 17 questions distributed into four sessions (demographic factors, perception of use of organs, reasons for disposal, and measures to favor their usage).

Liver transplantation after DRESS syndrome: A case report and review of the literature.

This study reports a patient with DRESS syndrome, associated with liver failure, treated with orthotopic liver transplantation.

The effects of profound hypothermia on pancreas ischemic injury: a new experimental model.

Objective: Pancreatic ischemia-reperfusion (IR) has a key role in pancreas surgery and transplantation. Most experimental models evaluate the normothermic phase of the IR. We proposed a hypothermic model of pancreas IR to evaluate the benefic effects of the cold ischemic phase.

Liver transplantation: fifty years of experience.

Since 1963, when the first human liver transplantation (LT) was performed by Thomas Starzl, the world has witnessed 50 years of development in surgical techniques, immunosuppression, organ allocation, donor selection, and the indications and contraindications for LT. This has led to the mainstream, well-established procedure that has saved innumerable lives worldwide. Today, there are hundreds of liver transplant centres in over 80 countries.

Small bowel transplantation.

Background: Small bowel transplantation evolution, because of its complexity, was slower than other solid organs. Several advances have enabled its clinical application.

Aim: To review intestinal transplantation evolution and its current status.

Portal vein thrombosis in liver transplantation.

Background: Portal vein thrombosis was considered a contraindication for liver transplantation in the past because of the high morbidity and mortality rates. Many advances made the results better.

Aim: Review the advances and surgical strategies for liver transplantation in presence of portal vein thrombosis.

Lower limb compartment syndrome associated with Lloyd-Davies/lithotomy position in colorectal surgery.

Lower limb compartment syndrome is a rare complication of surgical patients submitted to operation in the lithotomy/Lloyd-Davies position. The diagnosis and treatment of this feared complication should be promptly instituted otherwise the patient may have serious neuromuscular impairment, limb loss or even fatal outcome. Furthermore, rabdomyolysis and myoglobinuria may lead to acute renal failure.