Publications by authors named "Raegan Hunt"
Article Synopsis
- Pre-procedural antisepsis in neonatal intensive care units is crucial for preventing infections, but topical antiseptics can harm neonatal skin, and there's a lack of solid guidelines on their use.* -
- A systematic review of 19 studies showed that extremely preterm and very low birth weight infants are at high risk for skin injuries from antiseptics, particularly chlorhexidine.* -
- The main skin problems reported were erythema, skin breakdown, and chemical burns, highlighting the urgent need for better research and guidelines to protect this vulnerable population during medical procedures.*
Article Synopsis
- The study focused on afebrile infants under 60 days old who received dermatology consultations specifically for pustules and/or vesicles across six academic centers from 2013 to 2019.
- Out of 879 consultations, 183 infants were assessed; none showed serious bacterial infections, but 9 were diagnosed with herpes simplex virus (HSV) and 5 preterms had angioinvasive fungal infections.
- The findings indicate that for full-term afebrile infants, the risk of serious skin-related infections is low if HSV is ruled out, while preterm infants require thorough investigation due to higher risks.
Importance: Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic skin disease and association with mental health needs further study.
Objective: To examine the extent of stigma, dependence on disease visibility and severity, and association with mental health and quality of life (QOL) in chronic pediatric skin disease.
Article Synopsis
- Ulceration is a problem that can happen with a type of growth called infantile hemangioma (IH), and this study looks at severe cases of it.
- The researchers studied 35 patients and found that large hemangiomas with thin tops were most often linked to aggressive ulceration, especially in certain body areas.
- Understanding these different types of IH and their ulceration patterns can help doctors treat kids better by spotting which ones might have more serious problems.
Article Synopsis
- The study looked into what challenges parents face when trying to get their child diagnosed and treated for juvenile localized scleroderma and systemic sclerosis, which are rare skin conditions.
- Many parents said a big problem was that doctors don’t know enough about these conditions, making it hard to get the right care.
- Even though most families had good education and income, they still faced issues like long wait times, balancing everyday life with healthcare needs, and finding reliable information about their child’s condition.
Article Synopsis
- - Hematologic-associated eosinophilic pustular folliculitis (EPF) is a skin condition seen in patients with blood cancers, often arising after treatments like chemotherapy or transplants.
- - There are limited reports of this condition in children, highlighting its rarity in pediatric cases.
- - A case study is presented where a skin smear stained with Wright's method helped quickly confirm the diagnosis of hematologic-associated EPF through the identification of eosinophils.
Infantile hemangiomas are the most common childhood vascular lesions. LUMBAR syndrome (lower body hemangioma, urogenital abnormalities/ulceration, myelopathy, bony deformities, anorectal malformations/arterial anomalies, and rectal anomalies) warrants special treatment considerations. Here we describe a case of an infant with LUMBAR syndrome who presented with severe perineal ulceration refractory to standard medical therapy and was managed with a temporary diverting sigmoid colostomy.
View Article and Find Full Text PDFArticle Synopsis
- - Green nail syndrome (GNS) is a nail infection caused by Pseudomonas bacteria, leading to green discoloration, often affecting those with existing nail issues or who are frequently in wet environments.
- - The patient in the case developed GNS following home application of artificial nails, which contributed to the infection.
- - This case highlights the risks associated with prolonged use of artificial nails, especially in children, showcasing a rare but serious infection.
Importance: Ulceration is a common complication of infantile hemangioma (IH), which leads to substantial morbidity. Ulceration in IH has not been systematically studied since the advent of β-blocker therapy for IH.
Objectives: To examine treatment interventions used for ulceration in IH and identify clinical prognostic indicators of healing time.
Background: The distribution of pediatric-onset morphea and site-based likelihood for extracutaneous complications has not been well characterized.
Objective: To characterize the lesional distribution of pediatric-onset morphea and to determine the sites with the highest association of extracutaneous manifestations.
Methods: A retrospective cross-sectional study was performed.
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome is a rare autoinflammatory disorder. Cutaneous manifestations of CANDLE syndrome include characteristic recurring violaceous annular plaques comprised of an immature dermal mononuclear cell infiltrate. In CANDLE syndrome, deleterious genetic mutations inhibit proteasome-immunoproteasome function, resulting in cellular accumulation of ubiquitinated waste proteins that activate type I interferon signaling to drive inflammation.
View Article and Find Full Text PDFAplasia cutis congenita (ACC) is characterized by the complete or partial absence of skin at birth, with 85% of cases of ACC involving the scalp vertex. The etiology of ACC is unclear and appears to be multifactorial. We present the case of a 3-month-old boy who presented with a diagnosis of non-scalp ACC affecting approximately 80% of his total body surface area at birth.
View Article and Find Full Text PDFBackground: Treatment with BRAF inhibitors (BRAFI) and MEK inhibitors (MEKI) causes cutaneous reactions in children, limiting dosing or resulting in treatment cessation. The spectrum and severity of these reactions is not defined.
Objective: To determine the frequency and spectrum of cutaneous reactions in children receiving BRAFI and MEKI and their effects on continued therapy.
Article Synopsis
- Pediatric melanoma is rare and hard to diagnose, but it can be deadly in kids.
- In a study, most fatal cases were found in white and Hispanic patients, with an average diagnosis age of 12.7 years.
- Different types of melanoma were found, with many linked to moles present since birth, but there were no fatal cases of a specific type called spitzoid melanoma in children.
Objective: To characterize the clinical and histologic presentation of reactive granulomatous dermatitis (RGD) in the pediatric population.
Methods: In this multicenter retrospective chart review, 7 pediatric patients with biopsy-proven RGD were identified. Photographs, histology reports, and clinical course were reviewed to discover patterns in demographics, comorbid conditions, autoimmune sequelae, drug exposures, infections, morphology, and histologic features.
Purpose Of Review: Neonatal skin acclimates rapidly to dry, aerobic conditions at birth and skin function gradually matures throughout infancy. Gentle skin care practices support the ongoing development and function of newborn skin. This article reviews research updates and current skin care recommendations for full-term infants, premature infants, and infants born with severe cutaneous manifestations of genetic skin disorders.
View Article and Find Full Text PDFSlime has become extremely popular as a children's toy in recent years and is typically made with various household substances. Although reports of slime causing skin irritation are not uncommon, case reports of slime-induced allergic contact dermatitis have only recently surfaced. We present a case of a child with hand dermatitis, history of exposure to slime, and positive allergen patch testing to two ingredients found in slime.
View Article and Find Full Text PDFBackground: Epidemiological knowledge and predictors of melanoma among children and adolescents in multiethnic populations are limited.
Procedure: Using data from the Texas Cancer Registry (TCR) and the Surveillance, Epidemiology, and End Results (SEER) 13 database, we identified incident melanoma cases diagnosed at 0-20 years old during 1995-2013 in Texas and the United States, respectively. Using negative binomial regression, associations between demographic factors and melanoma incidence rates (IR) were evaluated by calculating incidence rate ratios (IRR) and 95% confidence intervals (CI).
The skin serves as a unique barrier from the outside world and undergoes critical changes during its development and maturation. This article reviews evidence-based recommendations for the routine care of newborn skin that should be integrated into the pediatrician's practice. [Pediatr Ann.
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