Management and Visual Outcomes of Acute Bacterial Endophthalmitis Following Intravitreal Injection of Contaminated Bevacizumab in a Single Day.

Background And Objective: Bevacizumab requires compounding for off-label intravitreal injection, thus creating a risk of possible contamination during preparation.

Patients And Methods: This retrospective, consecutive case series from a single site included patients who developed culture-proven acute endophthalmitis after intravitreal injection with contaminated bevacizumab. All patients suspected of endophthalmitis had vitreous biopsy and microbial cultures prior to initiation of treatment and were managed with immediate tap and injection of antibiotics followed early by pars plana vitrectomy.

Thyroid hormones, lipid profile and anthropometric changes after programmed weight loss in Palestinian obese adult females.

Objective: we aimed to investigate the changes in thyroid hormones, lipid profile and anthropometric measures after programmed weight loss in Palestinian obese adult females MATERIALS AND METHODS: This prospective study included 94 obese female (20-50 years old) as cases and 94 Non-obese of same age as controls for baseline comparisons. Obese female were assigned for low calorie diet (1200-1500 Kcal/day) in addition to a daily program of therapeutic exercise for six month. Parameters were measured, statistically analyzed and compared with control before and after study.