Publications by authors named "Raed J Zuhour"
Introduction: Insurance denials for clinical trials serve as a pertinent barrier for patients to remain trial-eligible, thus hindering the development of therapies and the overall advancement of health care. We present results from an ongoing oncology randomized clinical trial regarding insurance denials and peer-to-peer authorization (P2PA) success rate in allowing patients to remain trial-eligible.
Methods: The ongoing Spine Patient Optimal Radiosurgery Treatment for Symptomatic Metastatic Neoplasms Phase II trial randomizes spine cancer patients to treatment with spine radiosurgery/stereotactic body radiation therapy (SBRT) versus conventional external beam radiation therapy (EBRT).
Article Synopsis
- This study focuses on improving the delivery of cancer treatment by evaluating autosegmentation methods that outline key organs at risk (OARs) in head and neck cancer patients using low-resolution MRIs from a specific machine known as the MR-linac.
- Researchers investigated 20 autosegmentation approaches, including both population-based methods and deep learning techniques, comparing their effectiveness in accurately identifying OARs against established ground truth contours.
- Results showed varying performance across methods, with additional dosimetric analysis performed on the best and worst methods, highlighting the importance of accurate dose reconstruction for effective patient treatment.
Purpose: In the management of uveal melanoma, eye plaque brachytherapy (EPBT) has replaced enucleation as the standard of care for small size tumors that require treatment, and for medium size tumors. In the modern era, EPBT is being utilized more frequently for certain large tumors as well. While there is prospective randomized evidence to support utilization of EPBT for tumors of appropriate dimensions, it is unclear what the actual practice patterns are across the United States.
View Article and Find Full Text PDFPurpose: There is no current randomized data comparing the efficacy of brachytherapy and enucleation for patients with larger sized tumors. The purpose of the present study was to use a large, contemporary database to determine current practice patterns and compare survival outcomes between different management options for patients with choroidal melanoma of various sizes.
Material And Methods: The National Cancer Database was queried (2004-2014) for histologically-confirmed choroidal melanoma for patients treated with brachytherapy versus enucleation.