Publications by authors named "Radzi Abu Hassan"
Cost of SARS-CoV-2 self-test distribution programmes by different modalities: a micro-costing study in five countries (Brazil, Georgia, Malaysia, Ethiopia and the Philippines).
BMJ Open
April 2024
Article Synopsis
- The study evaluates the economic costs of providing COVID-19 self-testing in five different countries, aiming to improve access to testing three years into the pandemic.
- Results showed that the cost per self-test kit ranged from $2.44 to $12.78, influenced by the duration of implementation and demand, with a potential 50% price reduction bringing costs down to between $1.04 and $3.07.
- Key costs were largely driven by test procurement, accounting for 58-87% of expenses for off-site testing and 15-50% for on-site, with staffing costs being more significant for on-site self-testing.
Hepatitis B virus (HBV) is causally linked to hepatocellular injury and cell death, which are followed by hepatocellular carcinoma (HCC) after a long latent period. The HBV derived X protein (HBX) is the most potent carcinogenic factor for HCC, however, the molecular mechanism of HBX-induced transformation of hepatic cells in HCC is poorly understood. We have shown that nuclear receptor co-repressor (NCoR) is essential for the spatial repression of global transcription by the promyelocytic leukemia oncogenic domains (PODs), a frequent target of viral oncoproteins like HBX and that disintegration of PODs due to misfolded conformation dependent loss (MCDL) of NCoR is linked to promyelocytic and monocytic acute myeloid leukemia (AML).
View Article and Find Full Text PDFMalaysia is a country where an estimated 1 million people are chronically infected with hepatitis B virus (HBV) and an estimated 2.5% of the adult population are positive for antibody to hepatitis C virus (HCV). Effective nationwide vaccine coverage seems to be a highly effective measure to prevent new HBV infection.
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