Publications by authors named "Radu Fleaca"
The number of total hip and total knee replacements has increased steadily each year. Today, they are routinely performed all over the world. The increasing prevalence of obesity has led to an increase in the number of total knee arthroplasties (TKAs) performed in patients with a higher body mass index (BMI) and also has a higher rate of complications.
View Article and Find Full Text PDFAt present, it is necessary to identify specific biochemical, molecular, and genetic markers that can reliably aid in screening digestive cancer and correlate with the degree of disease development. Has-miR-129-5p is a small, non-coding molecule of RNA, circulating in plasma, gastric juice, and other biological fluids; it plays a protective role in tumoral growth, metastasis, etc. Furthermore, it is involved in various diseases, from the development of digestive cancer in cases of downregulation to neurodegenerative diseases and depression.
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- The gut microbiota plays a crucial role in a host's nutrition, immunity, and metabolism, and its imbalance (dysbiosis) is linked to various diseases.
- Fecal microbiota transplantation (FMT) is particularly effective in treating recurrent Clostridium difficile infections and is being explored for its potential benefits in other conditions, like inflammatory bowel diseases and cancers.
- Recent research highlights the promising role of FMT in managing cancer and its treatment-related complications, based on both preclinical and clinical evidence.
Introduction: The search for biomarkers has been central to efforts of improving clinical diagnosis and prognosis in psychopathology in the last decades. The main approach has been to validate biomarkers that could accurately discriminate between clinical diagnoses of very prevalent forms of psychopathology. One of the most popular electrophysiological markers proposed for discrimination in depressive disorders is the electroencephalography (EEG)-derived frontal alpha asymmetry.
View Article and Find Full Text PDFThe spread of the COVID-19 virus created more than a medical crisis, while it also negatively affected the mental health of the general population. This context increased the vulnerability of the psychiatric population. While research interest highly targeted vaccine hesitancy and acceptance, many studies focused on trust issues-both in vaccine efficacy and in communication with authorities.
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- Diabetes, particularly type 2, has seen a significant rise over the past decade, especially in developing countries, with increasing cases in younger adults.
- A study conducted in Romania aimed to create a risk score to assess the risk of amputation in patients with diabetic foot lesions, using clinical data from two local hospitals.
- Key risk factors identified include smoking, obesity, high blood sugar levels, long duration of diabetes, fatty liver, and heart diseases, all of which can worsen diabetic foot injuries and impact overall treatment effectiveness and quality of life.
Background And Objectives: Osteoporotic spine fractures represent a significant factor for decreasing quality of life in the elderly female population. Understanding the mechanisms involved in producing these fractures can improve their prevention and treatment. This study presents a biomechanical method to produce a vertebral fracture, conducted on a human spine segment, observing the displacements and strains in the intervertebral disc, endplate, and vertebral body.
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