Publications by authors named "Radu Apostol"
Objectives: To assess the degree to which removal of FDA' Pregnancy Categories (PC) of medications (A, B, C, and D) from labeling, affects the likelihood that providers will prescribe those medications.
Methods: Over a one-year period a convenience sample of providers was recruited into a randomized, survey-based, study. Two versions of the survey were randomly distributed; version 1 presented clinical vignettes, drug information, and PC, while version 2, presented the identical information without the PC.
Article Synopsis
- A recent survey shows that concerns about the spread of undetected cancer cells during gynecologic surgery have led to a significant decline in the use of power morcellators among surgeons.
- Among the surveyed gynecologic surgeons, 61% reported not using morcellators, with many citing hospital bans or unavailability as reasons, especially among less experienced surgeons.
- Despite the decreased use of morcellators, most surgeons continue to favor minimally invasive techniques, performing laparotomy in fewer than 25% of their cases.
Background And Objectives: To determine if surgery using ultrasonic energy for dissection results in less adhesion formation than monopolar electrosurgical energy in the late (8 weeks) postoperative period.
Methods: Injuries were induced in rabbits by using ultrasonic energy on one uterine horn and the adjacent pelvic sidewall and using monopolar energy on the opposite side. Eight weeks postoperatively, the rabbits underwent autopsy and clinical and pathologic scoring of adhesions was performed by blinded investigators.
New insights in the pathophysiology of ovarian cancer and implications for screening and prevention.
Am J Obstet Gynecol
September 2015
Despite advances in medicine, ovarian cancer remains the deadliest of the gynecological malignancies. Herein we present the latest information on the pathophysiology of ovarian cancer and its significance for ovarian cancer screening and prevention. A new paradigm for ovarian cancer pathogenesis presupposes 2 distinct types of ovarian epithelial carcinoma with distinct molecular profiles: type I and type II carcinomas.
View Article and Find Full Text PDFObjective: To study the distribution of ionized and total magnesium (Mg) in serum and cerebral spinal fluid (CSF) in preeclamptic women receiving MgSO(4) and how this treatment affects the ionized calcium (Ca(2+)) and ionized Ca:Mg ratios compared with healthy nonpregnant women and pregnant control women (HP).
Design: Controlled clinical study.
Setting: An academic medical center.