Publications by authors named "Radu Alexandru Vulpoi"

Article Synopsis
  • Novel direct oral anticoagulants (DOACs) like apixaban are widely used to treat non-valvular atrial fibrillation, but have been linked to adverse reactions such as esophagitis dissecans superficialis (EDS).
  • A case study of a 73-year-old woman revealed that after several weeks on apixaban, she experienced weakness, difficulty swallowing, and gastrointestinal bleeding, leading to a diagnosis of EDS.
  • The patient was treated with a proton pump inhibitor and iron supplements, and after recovery, opted for rivaroxaban instead of the initially suggested vitamin K antagonist for her anticoagulation therapy.
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Inflammatory bowel disease (IBD) comprises two types of chronic intestinal disorders: Crohn's disease and ulcerative colitis. In long-standing ulcerative colitis disease activity, histological persistent inflammation has been linked to an increased risk of relapse, and long-term corticosteroid use, even when endoscopic remission is reached. In Crohn's disease, the discontinuous nature of lesions and transmural inflammation have limited the standardized histological assessment.

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Irritable bowel syndrome (IBS) has a global prevalence of around 4.1% and is associated with a low quality of life and increased healthcare costs. Current guidelines recommend that IBS is diagnosed using the symptom-based Rome IV criteria.

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Globally, metabolic diseases such as obesity, type 2 diabetes mellitus and non-alcoholic fatty liver disease pose a major public health threat. Many studies have confirmed the causal relationship between risk factors and the etiopathogenesis of these diseases. Despite this, traditional therapeutic management methods such as physical education and diet have proven insufficient.

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Artificial intelligence, a computer-based concept that tries to mimic human thinking, is slowly becoming part of the endoscopy lab. It has developed considerably since the first attempt at developing an automated medical diagnostic tool, today being adopted in almost all medical fields, digestive endoscopy included. The detection rate of preneoplastic lesions (i.

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