Publications by authors named "Radu A Popescu"
Article Synopsis
- - The study tested scaffolds made of alginate-pullulan-bioactive glass-ceramic with different amounts of copper oxide in rats to see how well they could heal bone defects.
- - Results showed significant bone healing after 5 weeks, with the best results (37% new bone formation) coming from the scaffolds with 1.5 mol % copper oxide.
- - Overall, both scaffold types promoted new bone growth, indicating that these composite materials have strong potential for use in tissue engineering.
Composites based on sodium alginate, pullulan, and bioactive SiO -CaO-P O glass-ceramics with copper oxide were prepared as capsules. The obtained samples were structurally characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM), and their bioactivity and biocompatibility properties were also tested both in vitro and in vivo by XRD, FT-IR, SEM, and high-resolution transmission electron microscopy. The fibroblast and osteoblast cell viability assays have shown good proliferation rates for all investigated samples, whereas all composites exhibited a good in vivo tolerance.
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