Publications by authors named "Radka Nikolova"

Article Synopsis
  • Autologous hemopoietic stem cell transplantation is a treatment option for both malignant and non-malignant conditions, but it comes with a heightened risk of infections early and late after the procedure.
  • A study analyzing 699 patients found that 69.8% experienced neutropenic fever, with most infections being bacteremia, particularly prevalent in lymphoma patients compared to those with plasma cell disorders.
  • Early infections, especially bacteremia, were linked to increased mortality risk, emphasizing the need for effective preventative measures and treatments in patients undergoing this type of transplantation.*
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Streptococcal toxic shock syndrome (STSS) is a hyperacute, life-threatening illness, a complication of invasive streptococcal (mostly group A, rarely groups B, G or C) infection. There is no portal of entry (skin, vagina, pharynx) in nearly half of the STSS cases. The initial signs and symptoms (fever, flu-like complaints, hypotension) are scarce and aspecific, but because of its rapid progression and poor prognosis, early high level of suspicion is necessary.

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Enterobiasis is an easily recognizable and treatable disease with higher incidence among children. Based on these facts, its clinical importance is usually underestimated. This infection also occurs during adulthood and without treatment, it can cause severe complications in some rare cases.

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Unlabelled: Zygomycosis (mucormycosis) is a rare, highly aggressive opportunistic fungal disease caused by saprophytic fungi, belonging to the division Zygomycota, class Zygomycetes. Patients with immunodeficiency, neutropenia, iron overload, hematological malignancies, as well as diabetics with ketoacidosis are typically affected.

Case Presentation: Authors describe the case of an eighteen-year old man with poor compliance suffering from diabetes since the age of nine.

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The ARTEMIS Global Antifungal Susceptibility Program provides the collection of epidemiological data and the results of the fluconazole and voriconazole susceptibility testing of yeast isolates. Participating in this study, a total of 7318 clinical yeast isolates were tested from different geographical areas in Hungary in the period 2001 to 2003. The species isolated most frequently was C.

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Over recent years the clinical importance of invasive fungal infections has significantly increased. Mucormycosis refers to a rare, life threatening, opportunistic disease caused by filamentous fungi of the order Mucorales. Most frequently mucormycosis occurs in patients with ketoacidotic diabetes and in neutropenic patients with acute leukaemia.

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