Publications by authors named "Radim Spacek"
Article Synopsis
- Extracorporeal cardiopulmonary resuscitation (ECPR) utilizes extracorporeal membrane oxygenation (ECMO) to support patients experiencing refractory cardiac arrest, with survival outcomes heavily influenced by the patient's age.* -
- Younger patients typically show better survival and neurological outcomes with ECPR, stressing the importance of age in clinical decision-making alongside other factors.* -
- The review highlights disparities in survival rates between in-hospital and out-of-hospital cardiac arrests and discusses the potential of artificial intelligence in creating predictive models, while also raising ethical questions related to age-based treatment.*
Article Synopsis
- Acute pericarditis can be life-threatening and is not always easy to diagnose, while hiatal hernia is often asymptomatic but can lead to serious complications if advanced.
- A 74-year-old woman presented with chest pain and was initially treated for pneumonia but later diagnosed with a large hiatal hernia and purulent pericarditis after imaging tests.
- During surgery, doctors discovered a fistula between the heart and colon, leading to severe septic shock and the patient's death shortly after the operation, underscoring the need for collaborative medical approaches in complex cases.
Article Synopsis
- - The PROTOCOLENERGY trial compared two methods for cardioversion of atrial fibrillation: a stepwise escalating energy algorithm (RaA) and a maximum fixed energy algorithm (MfA), with 300 patients receiving treatment.
- - The results revealed similar success rates for establishing sinus rhythm at both 1 minute and 2 hours, but RaA led to fewer skin complications due to its lower starting energy shock.
- - The study concluded that while both protocols are effective, RaA is particularly advantageous for patients with a body mass index less than 29 to 34 kg/m, as it reduces skin redness after treatment.
Background: For the treatment of patients with electrical storm (ES), we established a two-step algorithm comprising standard anti-arrhythmic measures and early ultrasound-guided stellate ganglion blockade (SGB). In this single-center study, we evaluated the short-term efficacy of the algorithm and tested the hypothesis that early SGB might prevent the need for intubations.
Methods: Overall, we analyzed data for 70 ES events in 59 patients requiring SGB (mean age 67.
Background: Refractory angina pectoris (AP) significantly impairs quality of life in patients with chronic coronary syndrome. Several minimally invasive methods (coronary sinus reducer, cell therapy, laser or shockwave revascularization, and spinal cord stimulation) or non-invasive methods (external counterpulzation) have been studied. However, their routine clinical use has not been widely implemented.
View Article and Find Full Text PDFDifferences in risk profiles and long-term outcomes in acute heart failure patients with preserved and reduced left ventricular ejection fraction in the Czech Republic: The AHEAD registry sub-analysis.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
March 2021
Background: The latest European heart failure guidelines define patients as those with reduced (HFrEF), mid-range, and preserved (HFpEF) left ventricular ejection fraction (LVEF; <40%, 40%-49%, and ≥50%, respectively). We investigated the causes of rehospitalizations/deaths in our institution's heart failure patients and focused on differences in the clinical presentation, risk profile, and long-term outcomes between the HFrEF and HFpEF groups in a real-life scenario.
Methods And Results: We followed 1274 patients discharged from heart failure hospitalization in 2 centres.
Aims: To assess the possible merits of optical coherence tomography (OCT) guidance in primary percutaneous coronary intervention (pPCI).
Methods And Results: 201 patients with ST-elevation myocardial infarction (STEMI) were enrolled in this study. Patients were randomized either to pPCI alone (angio-guided group, n=96) or to pPCI with OCT guidance (OCT-guided group, n=105) and also either to biolimus A9 or to everolimus-eluting stent implantation.
Objective: To investigate a potential relationship between implantable cardioverter defibrillator (ICD) therapies and daily geomagnetic activity (GMA) recorded in a large database.
Patients And Methods: The ALTITUDE database, derived from the Boston Scientific LATITUDE remote monitoring system, was retrospectively analyzed for the frequency of ICD therapies. Daily GMA was expressed as the planetary K-index and the integrated A-index and was graded as levels I (quiet), II (unsettled), III (active), and IV (storm).
Background: The objective of our study was to assess whether optical coherence tomography (OCT) guidance could guide intervention to avoid balloon angioplasty and stenting during primary percutaneous coronary intervention.
Methods: One hundred patients with ST-segment elevation myocardial infarction and thrombus-containing lesion were enrolled in this study. Thrombus aspiration was performed in all cases followed by an OCT study.
Purpose: The aim of this trial was to assess the feasibility and safety of endothelial progenitor cells capture (EPC) stent in the treatment of acute ST-elevation myocardial infarction (STEMI) when compared with cobalt-chromium stents (CoCr).
Methods: Between July 2006 and May 2008, 100 patients with single vessel disease undergoing primary PCI for STEMI were randomly assigned to receive either EPC stent (N = 50) or CoCr stent (N = 50). High-pressure stent implantation was carried out in both groups.
Objective: To assess the role of the intravascular ultrasound (IVUS) during implantation of drug-eluting stents (DES) on long-term outcome in patients with complex coronary artery disease and high clinical risk profile with special attention to the development of late stent thrombosis (LST).
Methods: Two hundred and ten patients were randomly assigned to receive DES either with (N = 105) or without (N = 105) the IVUS guidance. Dual antiplatelet treatment was administered for 6 months in all patients.
Background: The aim of this study was to compare the use of classic bare- metal stents with dedicated bifurcation bare-metal stents in patients who were not eligible for drug-eluting stents (DES) implantation.
Methods: Sixty patients with bifurcation stenosis were randomly assigned to received either a dedicated bifurcation or a bare-metal stent (n = 30) or classic bare-metal stent (n = 30) with stenting of the parent vessel and angioplasty/or provisional stenting of the side branch. Fifty-nine patients underwent 12-month clinical and angiographic follow up unless this was performed earlier due to symptoms.
The authors present a fatal case of late thrombosis of paclitaxel-eluting stent implanted in the left main stem occurring 6 months after the procedure and 3 weeks after the cessation of clopidogrel. An autopsy has shown the lack of endothelization of deployed stent.
View Article and Find Full Text PDFBackground: The aim of this study was to assess neointimal hyperplasia following sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) implantation in a patients with complex coronary disease.
Method: Between January to December 2004, 70 patients were enrolled in this study (SES = 37; PES = 33. The primary objective was to assess the efficacy of SES and PES on neointimal proliferation inhibition in patients with complex coronary lesions by volumetric 3D intravascular ultrasound (IVUS) assessment at six-month follow-up.