Publications by authors named "Radhakrishnan Vidya"

The sensor, derived from a triazole-substituted acridinedione, exhibits distinct responses to Cu⁺ and Fe³⁺ ions. It shows fluorescence enhancement in the presence of Cu⁺ ions and a reduction in fluorescence with Fe³⁺ ions. This sensor is distinguished by its high sensitivity, selectivity, rapid response time, reversibility, and broad operating pH range, with shallow detection limits for both ions.

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One of the global challenges for living things is to provide pollution and harmful microbes-free environment. In this study, magnetically retrievable spinel-structured manganese zinc ferrite (MnZnFeO) (MZF) was synthesized by a facile solvothermal method. Further, the MZF with different weight percentages (10 wt%, 50 wt%, and 80 wt%) were supported on reduced graphene oxide (rGO).

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Diabetes is a prevalent metabolic disorder associated with various complications. Inhibition of α-glucosidase and α-amylase enzymes is an effective strategy for managing non-insulin-dependent diabetes mellitus. This study aimed to investigate the antioxidant and antidiabetic potential of Ormocarpum cochinchinense leaf through in vitro and in silico approaches.

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Nutrient deficiencies are a major problem that is prone to affect millions of people around the globe. Biofortification, a process of enriching nutrients in staple food crops is an effective method to tackle this malnutrition-associated disorder. Tomato () is a globally consumed crop and therefore is a suitable candidate for biofortification.

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Agriculture sector is facing a lot of constraints such as climate change, increasing population and the use of chemicals, and fertilizers which have significant influence on sustainability. The excessive usage of chemical fertilizers and pesticides has created a significant risk to humans, animals, plants, and the environment. To reduce the dependency on chemical fertilizers and pesticides a biological-based alternative is required.

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The active and inexpensive catalyst cupric oxide (CuO) loaded foliar fertilizer of graphitic carbon nitride (-CN) is investigated for biological applications due to its low cost and easy synthesis. The synthesized CuO NPs, bulk g-CN, exfoliated -CN, and different weight percentages of 30 wt%, 40 wt%, 50 wt%, 60 wt%, and 70 wt% CuO-loaded -CN are characterized using different analytical techniques, including powder X-ray diffraction, scanning electron microscopy, energy dispersive X-ray analysis, and ultraviolet-visible spectroscopy. The nanocomposite of CuO NPs loaded -CN exhibits antibacterial activity against Gram-positive bacteria ( and ) and Gram-negative bacteria ( and ).

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Aims: The present investigation was aimed at exploring the phytoconstituents using Gas Chromatography Mass Spectroscopy and to evaluate antioxidant and anti-inflammatory properties of the leaf extracts.

Materials And Methods: The extracts were obtained sequentially with petroleum ether, ethyl acetate and water using Soxhlet apparatus. The anti-inflammatory property of the identified compounds using GC- MS spectroscopy was evaluated in silico.

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Article Synopsis
  • - The study focused on creating silver nanoparticles using the red algae Portieria hornemannii, which displayed a color change and produced distinct absorbance peaks at 418 nm when analyzed.
  • - Additional characterization techniques, like Fourier transform infrared spectroscopy and X-ray diffraction, confirmed the nanoparticles' functional groups and crystal structure, while microscopy showed the nanoparticles were mainly spherical in shape.
  • - The synthesized silver nanoparticles exhibited significant antimicrobial activity against several fish pathogens, specifically showing the highest effectiveness against Vibrio harveyii and Vibrio parahaemolyticus, suggesting a potential eco-friendly alternative to traditional antibiotics in aquaculture.
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In the present study, an efficient biosurfactant producing bacterial strain MKVIT3 was isolated from an oil logging area in Vellore district of Tamil Nadu, India. Liquid chromatography-mass spectrometry (LC-MS/MS) analysis was performed for the identification of different congeners present in the extracted biosurfactant. The column purified biosurfactant was used to stabilise the formation of silver nanoparticles (NP) using borohydrate reduction in reverse micelles.

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This study was conducted to assess the anti-inflammatory effect of a novel synthesized phenanthridine alkaloid (PHE-4i) and to examine the possible involvement of hydrogen sulfide (H2S) in anti-inflammatory mechanism. The synthesized phenanthridine derivative PHE-4i (2, 5, and 10 mg/kg) was administered intraperitoneally to rats. One hour following treatment, inflammation was induced by intraplantar injection of carrageenan (1 %), in the hind paw.

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Cobalt-doped iron oxide nanoparticles were prepared by solution combustion technique. The structural and magnetic properties of the prepared samples were also investigated. The average crystallite size of cobalt ferrite (CoFe2O4) magnetic nanoparticle was calculated using Scherrer equation, and it was found to be 16±5 nm.

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