Publications by authors named "Radha Paturu"
Article Synopsis
- The study aimed to test for EGFR, ALK, ROS1, and MET genetic alterations in tissue and blood samples from treatment-naïve NSCLC patients and analyze their impact on overall survival.
- A total of 100 patients were evaluated; results showed that 61 had genetic changes in tissue samples, with EGFR mutations being most common, while plasma tests had lower sensitivity and specificity.
- The findings indicate that using both tissue and plasma testing improves EGFR mutation detection rates and can guide treatment decisions, enhancing overall survival for patients receiving targeted therapy.
Introduction: Ampullary adenocarcinoma is a rare neoplasm often treated by the complex Whipple's procedure. Several histological factors predict poor prognosis including pancreatobiliary morphology, presence of lymphovascular, perineural invasion and local or distant metastasis. Systemic therapy with gemcitabine, 5-fluorouracil regimens are given with variable benefits.
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