Conventional cancer therapies, including chemotherapy, radiotherapy, and immunotherapy, have significantly advanced cancer treatment. However, these modalities often face limitations such as systemic toxicity, lack of specificity, and the emergence of resistance. Recent advancements in genetic engineering and synthetic biology have rekindled interest in using bacteria as a novel therapeutic approach in oncology.
View Article and Find Full Text PDFDr. Gagandeep Kang is a towering personality in the field of microbiology and is known for her groundbreaking work globally. She made seminal discoveries in areas of enteric infections, vaccine development, and public health that have created a sea of change in scientific understanding and healthcare, probably beyond the borders of India.
View Article and Find Full Text PDFFor people with diabetes, diabetic foot ulcers (DFUs) are a serious condition that can result in amputations, among other dire consequences. This case report details the clinical course and management of a 40-year-old male with type II diabetes mellitus presenting with recurrent DFUs and blackening of the toes. Despite initial surgical intervention and aggressive antimicrobial therapy, the patient experienced persistent infection and graft failure, necessitating multiple treatments and ongoing care.
View Article and Find Full Text PDF, also known as , is a low-virulence, non-fermenter gram-negative bacillus mainly found in marine environments. We report a detailed series of four high-risk cases of septicemia with the common variable of positive blood cultures for . All four blood isolates were multi-drug resistant and susceptible to meropenem and trimethoprim-sulfamethoxazole.
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