Publications by authors named "Radek Debiec"
Heart failure (HF) is a clinical syndrome consisting of typical symptoms and signs due to structural and/or functional abnormalities of the heart, resulting in elevated intracardiac pressures and/or inadequate cardiac output. The vascular system plays a crucial role in the development and progression of HF regardless of ejection fraction, with endothelial dysfunction (ED) as one of the principal features of HF. The main ED manifestations (i.
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- Exercise intolerance is a common issue in heart failure with preserved ejection fraction (HFpEF), leading to a lower quality of life and higher rates of hospitalization and mortality.
- * The cardiopulmonary exercise test is crucial for measuring exercise tolerance and understanding the specific causes of limitations in patients with HFpEF, which can guide treatment.
- * Exercise training programs can enhance exercise tolerance in HFpEF patients, but more research is needed to determine the most effective types and durations of these programs.*
Background: Remote ischaemic conditioning (rIC) is a cardioprotective tool which has shown promise in preclinical and clinical trials in the context of acute ischaemia. Repeated rIC post myocardial infarction may provide additional benefits which have not previously been tested clinically.
Methods: The trial assessed the role of daily rIC in enhancing left ventricular ejection fraction (LVEF) recovery in patients with impaired LVEF (<45%) after ST segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (P-PCI).