Publications by authors named "Rachita Dhura"
Background: Androgenetic alopecia (AGA) is common. While topical minoxidil remains the only FDA-approved therapeutic for AGA, its efficacy is limited in stimulating clinically significant hair regrowth over the longer term. Oral minoxidil, which is used off-label, is a promising alternative; however, its effectiveness and underlying mechanisms warrant further investigation.
View Article and Find Full Text PDFArticle Synopsis
- - Minoxidil is the only FDA-approved topical treatment for androgenetic alopecia (hair loss), showing effectiveness in 30%-40% of users, especially 50% of men, but its success depends on its conversion by the enzyme SULT1A1.
- - The study aimed to identify and characterize the activity of SULT1A1 in various plant extracts to potentially enhance minoxidil's effectiveness.
- - Out of 10 botanical extracts tested, seven showed significant SULT1A1 activity, suggesting they could be used as natural supplements to improve minoxidil response in hair loss treatments.