Publications by authors named "Rachit S Mukkamala"
Article Synopsis
- Coordination of cellular signaling and adaptive metabolism is crucial for energy balance and homeostasis, with phosphorylation being a key regulatory mechanism for metabolic networks.
- The study categorizes phosphorylation sites on metabolic enzymes, finding that many are located near functional areas and emphasizing ones on oxidoreductases, particularly phosphotyrosine sites linked to enzyme function.
- Using a high fat diet model, the research uncovers sex-specific changes in metabolic regulation and identifies specific phosphotyrosine sites that predict metabolic responses, revealing how they influence enzyme activity and metabolic pathways.
